Intraoperative Magnetic Resonance Imaging in Brain Glioma Surgery Using Low-field system. Presentation of the First Twenty-eight Procedures

Main Article Content

Roberto Rafael Herrera, MD José Luis Ledesma, MD Héctor Pablo Rojas, MD Francisco Sanz, MD Juan Martin Herrera, MD Ariel Estramiana, MD Juan Santiago Bottan, MD

Abstract

Background: Imaging systems placed into the operating theatre is becoming a standard practice in glioma resection surgery.


Aim: To evaluate feasibility, safety, and utility of an intraoperative open low-field magnetic resonance imaging (iMRI) to assess the extent of glioma resection.


Methods: Study population sample included 28 patients undergoing first time surgical resection for brain gliomas. All patients underwent preoperative and postoperative high-field MRI scans, and one to four intraoperative MRI acquisitions, using a side-opening 0.25 T MRI system. Pre- and postoperative MRI scans were assessed to measure volumetric changes and the extent of resection. Surgical timing was also registered.


Results: n=28 patients (19 men and 9 women, range: 6 - 71 years), underwent microsurgical resection of brain glioma for the first time (18 high-grade and 10 low-grade gliomas). Postoperative MRI indicated that gross total resection (>99%) was achieved in 23/28 (82%), subtotal resection (90-99%) in 4/28 (14%) patients; in the latter, residual tumor volume ranges between 0.5 and 8.2 cm3; and partial resection (<90%) in 1/28 (4%). Three patients (10.7%) experienced worsening of neurological symptoms (only one permanent). The average time required for each imaging session was 12 minutes.


Conclusion and Relevance: Intraoperative low-field MRI-guided resections maximizes the extent of glioma resections, without significant interferences with surgical and anesthesiologic procedures and without excessive prolongation of the surgery, playing a relevant role in patient survival and quality of life.

Keywords: intra-operative magnetic resonance, glioma, extent of resection

Article Details

How to Cite
HERRERA, Roberto Rafael et al. Intraoperative Magnetic Resonance Imaging in Brain Glioma Surgery Using Low-field system. Presentation of the First Twenty-eight Procedures. Medical Research Archives, [S.l.], v. 12, n. 6, june 2024. ISSN 2375-1924. Available at: <https://esmed.org/MRA/mra/article/view/5387>. Date accessed: 22 july 2024. doi: https://doi.org/10.18103/mra.v12i6.5387.
Section
Research Articles

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