Glycemic Index of Vidavance®, a High Protein and High Fiber Oral Snack Replacement Therapy for Diabetes Patients
Main Article Content
Abstract
Background: Food products with a low Glycemic index (GI) and low Glycemic load (GL) help control blood glucose levels, and reduce the risk of diabetes-related morbidity and mortality. Vidavance®, an oral nutritional supplement (ONS) and Medical Nutrition Therapy (MNT) for pre-diabetes and diabetes has high-quality protein blend (soy protein isolate, calcium caseinate), dietary fiber (polydextrose, soy fiber), modified maltodextrin, chromium, and zinc, which are known to influence blood glucose control.
Aim: To determine the GI and GL of the Vidavance® in 31 people with diabetes (T2DM) aged 18 to 60 years, with fasting blood glucose (FBG) >120 mg / dL.
Methodology: The study participants consumed reference food (27.5 g of glucose monohydrate dissolved in 125 ml of water) followed by a three-day washout period. Then Vidavance® test dose (53 g available carbohydrate/100 gm) was given as 47.1.g of ONS mixed in 100 ml water to make up 390 ml). Continuous Glucose Monitoring reading was taken at 0, 15, 30, 45, 60, 90, and 120 minutes after the start of the test meal. The GI was assessed using a validated protocol by FAO and ISO (2010).
Results: 30 participants completed the study, (Mean age 55.2 ± 13.0 years.). The GI of the test food (Vidavance®) was 30.57 (low GI). No hyperglycemic events were observed during the study. The GI value was not influenced by age (years), sex, previous day’s dietary intake energy (kcal), and physical activity level. The GL of the test food was 3.85 (low GL).
Conclusion: Vidavance® is a low GI and low GL ONS and hence suitable for diabetic subjects.
Keywords:
Glycemic index, nutritional supplement, weight loss, diabetes, CGM
Article Details
How to Cite
M, Sabharwal et al.
Glycemic Index of Vidavance®, a High Protein and High Fiber Oral Snack Replacement Therapy for Diabetes Patients.
Medical Research Archives, [S.l.], v. 12, n. 7, aug. 2024.
ISSN 2375-1924.
Available at: <https://esmed.org/MRA/mra/article/view/5420>. Date accessed: 21 dec. 2024.
doi: https://doi.org/10.18103/mra.v12i7.5420.
Section
Research Articles
The Medical Research Archives grants authors the right to publish and reproduce the unrevised contribution in whole or in part at any time and in any form for any scholarly non-commercial purpose with the condition that all publications of the contribution include a full citation to the journal as published by the Medical Research Archives.
References
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29. Bhupathiraju SN, Tobias DK, Malik VS, et al. Glycemic index, glycemic load, and risk of type 2 diabetes: results from 3 large US cohorts and an updated meta-analysis. Am J Clin Nutr. 2014;100(1):218-232. doi:10.3945/ajcn.113.079533
30. Yeomans MR, Gray RW, Conyers TH. Maltodextrin preloads reduce food intake without altering the appetiser effect. Physiol Behav. 1998;64(4):501-506. doi:10.1016/s0031-9384(98)00086-9
31. Livesey G, Tagami H. Interventions to lower the glycemic response to carbohydrate foods with a low-viscosity fiber (resistant maltodextrin): meta-analysis of randomized controlled trials. Am J Clin Nutr. 2009;89(1):114-125. doi:10.3945/ajcn.26842
32. Sadakiyo T, Ishida Y, Inoue S ichiro, et al. Attenuation of postprandial blood glucose in humans consuming isomaltodextrin: carbohydrate loading studies. Food Nutr Res. 2017;61(1):1325306. doi:10.1080/16546628.2017.1325306
33. Jie Z, Bang-Yao L, Ming-Jie X, et al. Studies on the effects of polydextrose intake on physiologic functions in Chinese people. Am J Clin Nutr. 2000;72(6):1503-1509. doi:10.1093/ajcn/72.6.1503
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35. Meena PC, Kumar S, Srinivas K, et al. Great Indian Food Paradox: Trends and Patterns. Agri Econ Rese Revi. 2016;29(conf):31. doi:10.5958/0974-0279.2016.00031.8
36. Raji A, Seely EW, Arky RA, Simonson DC. Body fat distribution and insulin resistance in healthy Asian Indians and Caucasians. J Clin Endocrinol Metab. 2001;86(11):5366-5371. doi:10.1210/jcem.86.11.7992
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39. Nisak MB, Ruzita AT, Norimah AK, Azmi KN, Fatimah A. Acute Effect of Low and High Glycemic Index Meals on Post-prandial Glycemia and Insulin Responses with Type 2 Diabetes Mellitus. Malaysian Journal of Medicine and Health Sciences. 2009;5(1):11-20. Accessed March 17, 2022. http://wprim.whocc.org.cn/admin/article/articleDetail?WPRIMID=628073&articleId=628073
40. Vlachos D, Malisova S, Lindberg FA, Karaniki G. Glycemic Index (GI) or Glycemic Load (GL) and Dietary Interventions for Optimizing Postprandial Hyperglycemia in Patients with T2 Diabetes: A Review. Nutrients. 2020;12(6). doi:10.3390/nu12061561
2. Singer ME, Dorrance KA, Oxenreiter MM, Yan KR, Close KL. The type 2 diabetes ‘modern preventable pandemic’ and replicable lessons from the COVID-19 crisis. Preventive Medicine Reports. 2022;25:101636. doi:10.1016/j.pmedr.2021.101636
3. Pradeepa R, Mohan V. Epidemiology of type 2 diabetes in India. Indian Journal of Ophthalmology. 2021;69(11):2932-2938. doi:10.4103/ijo.IJO_1627_21
4. Mohan V. Why are Indians more prone to diabetes? J Assoc Physicians India. 2004;52:468-474.
5. Kapoor N, Sahay R, Kalra S, et al. Consensus on Medical Nutrition Therapy for Diabesity (CoMeND) in Adults: A South Asian Perspective. Diabetes Metab Syndr Obes. 2021;14:1703-1728. doi:10.2147/DMSO.S278928
6. Anjana RM, Unnikrishnan R, Deepa M, et al. Achievement of guideline recommended diabetes treatment targets and health habits in people with self-reported diabetes in India (ICMR-INDIAB-13): a national cross-sectional study. The Lancet Diabetes & Endocrinology. 2022;10(6):430-441. doi:10.1016/S2213-8587(22)00072-9
7. Thomas D, Elliott EJ. Low glycaemic index, or low glycaemic load, diets for diabetes mellitus. Cochrane Database Syst Rev. 2009;2009(1):CD006296. doi:10.1002/14651858.CD006296.pub2
8. Wolever TMS, Gibbs AL, Chiasson JL, et al. Altering source or amount of dietary carbohydrate has acute and chronic effects on postprandial glucose and triglycerides in type 2 diabetes: Canadian trial of Carbohydrates in Diabetes (CCD). Nutr Metab Cardiovasc Dis. 2013;23(3):227-234. doi:10.1016/j.numecd.2011.12.011
9. Misra A, Singhal N, Sivakumar B, Bhagat N, Jaiswal A, Khurana L. Nutrition transition in India: Secular trends in dietary intake and their relationship to diet-related non-communicable diseases. Journal of Diabetes. 2011;3(4):278-292. doi:10.1111/j.1753-0407.2011.00139.x
10. Veena N, Surendranath B, Arora S. Polydextrose as a Functional Ingredient and its Food Applications: A Review. IJDS. 2016;69(3):239-251. doi:10.5146/IJDS.V69I3.51101.G24364
11. Olli K, Salli K, Alhoniemi E, et al. Postprandial effects of polydextrose on satiety hormone responses and subjective feelings of appetite in obese participants. Nutrition Journal. 2015;14(1):2. doi:10.1186/1475-2891-14-2
12. Soong YY, Lim WX, Leow MKS, Siow PC, Teh AL, Henry CJ. Combination of soya protein and polydextrose reduces energy intake and glycaemic response via modulation of gastric emptying rate, ghrelin and glucagon-like peptide-1 in Chinese. Br J Nutr. 2016;115(12):2130-2137. doi:10.1017/S0007114516001689
13. Alptekin İM, Erdoğan E, İşler A, Yanalak EC, Çakiroğlu FP, Aras S. Short-term effects of milkshake containing polydextrose and maltodextrin on subjective feelings of appetite, energy intake and blood glucose in healthy females. Nutrition & Food Science. 2021;52(1):151-162. doi:10.1108/NFS-02-2021-0082
14. Pesta DH, Samuel VT. A high-protein diet for reducing body fat: mechanisms and possible caveats. Nutrition & Metabolism. 2014;11. doi:10.1186/1743-7075-11-53
15. Havel PJ. A scientific review: the role of chromium in insulin resistance. Diabetes Educ. 2004;Suppl:2-14.
16. Rajendran K, Manikandan S, Nair LD, et al. Serum Chromium Levels in Type 2 Diabetic Patients and Its Association with Glycaemic Control. J Clin Diagn Res. 2015;9(11):OC05-OC08. doi:10.7860/JCDR/2015/16062.6753
17. Miao X, Sun W, Miao L, et al. Zinc and Diabetic Retinopathy. J Diabetes Res. 2013;2013:425854. doi:10.1155/2013/425854
18. Brouns F, Bjorck I, Frayn KN, et al. Glycaemic index methodology. Nutr Res Rev. 2005;18(1):145-171. doi:10.1079/NRR2005100
19. Ceriello A. Postprandial hyperglycemia and diabetes complications: is it time to treat? Diabetes. 2005;54(1):1-7. doi:10.2337/diabetes.54.1.1
20. International Standards Organization. ISO 26642-2010 Food Products Determination of the Glycemic Index (GI) and Recommendation for Food Classification. International Standards Organization; 2010. Accessed March 16, 2022. https://www.iso.org/cms/render/live/en/sites/isoorg/contents/data/standard/04/36/43633.html
21. FAO/WHO. Carbohydrates in human nutrition. Report of a Joint FAO/WHO Expert Consultation. FAO Food Nutr Pap. 1998;66:1-140.
22. Atkinson FS, Foster-Powell K, Brand-Miller JC. International Tables of Glycemic Index and Glycemic Load Values: 2008. Diabetes Care. 2008;31(12):2281-2283. doi:10.2337/dc08-1239
23. Schwingshackl L, Hoffmann G. Long-term effects of low glycemic index/load vs. high glycemic index/load diets on parameters of obesity and obesity-associated risks: A systematic review and meta-analysis. Nutrition, Metabolism and Cardiovascular Diseases. 2013;23(8):699-706. doi:10.1016/j.numecd.2013.04.008
24. Ceriello A, Colagiuri S. International Diabetes Federation guideline for management of postmeal glucose: a review of recommendations. Diabet Med. 2008;25(10):1151-1156. doi:10.1111/j.1464-5491.2008.02565.x
25. Misra A, Sharma R, Gulati S, et al. Consensus Dietary Guidelines for Healthy Living and Prevention of Obesity, the Metabolic Syndrome, Diabetes, and Related Disorders in Asian Indians. Diabetes technology & therapeutics. 2011;13:683-694. doi:10.1089/dia.2010.0198
26. American Diabetes Association. Postprandial Blood Glucose. Diabetes Care. 2001;24(4):775-778. doi:10.2337/diacare.24.4.775
27. International Diabetes Federation. IDF Diabetes Atlas. Seventh edition. International Diabetes Federation; 2015. https://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=&cad=rja&uact=8&ved=2ahUKEwjimuLmzaL7AhWCSWwGHW1NBcgQFnoECAkQAQ&url=https%3A%2F%2Fwww.idf.org%2Fcomponent%2Fattachments%2Fattachments.html%3Fid%3D728%26task%3Ddownload&usg=AOvVaw0iHD15k39yaQoal5zPvBt0
28. Dharmalingam M, Das R, Jain S, et al. Impact of Partial Meal Replacement on Glycemic Levels and Body Weight in Indian Patients with Type 2 Diabetes (PRIDE): A Randomized Controlled Study. Diabetes Ther. 2022;13(9):1599-1619. doi:10.1007/s13300-022-01294-0
29. Bhupathiraju SN, Tobias DK, Malik VS, et al. Glycemic index, glycemic load, and risk of type 2 diabetes: results from 3 large US cohorts and an updated meta-analysis. Am J Clin Nutr. 2014;100(1):218-232. doi:10.3945/ajcn.113.079533
30. Yeomans MR, Gray RW, Conyers TH. Maltodextrin preloads reduce food intake without altering the appetiser effect. Physiol Behav. 1998;64(4):501-506. doi:10.1016/s0031-9384(98)00086-9
31. Livesey G, Tagami H. Interventions to lower the glycemic response to carbohydrate foods with a low-viscosity fiber (resistant maltodextrin): meta-analysis of randomized controlled trials. Am J Clin Nutr. 2009;89(1):114-125. doi:10.3945/ajcn.26842
32. Sadakiyo T, Ishida Y, Inoue S ichiro, et al. Attenuation of postprandial blood glucose in humans consuming isomaltodextrin: carbohydrate loading studies. Food Nutr Res. 2017;61(1):1325306. doi:10.1080/16546628.2017.1325306
33. Jie Z, Bang-Yao L, Ming-Jie X, et al. Studies on the effects of polydextrose intake on physiologic functions in Chinese people. Am J Clin Nutr. 2000;72(6):1503-1509. doi:10.1093/ajcn/72.6.1503
34. Wilding JPH. The importance of weight management in type 2 diabetes mellitus. Int J Clin Pract. 2014;68(6):682-691. doi:10.1111/ijcp.12384
35. Meena PC, Kumar S, Srinivas K, et al. Great Indian Food Paradox: Trends and Patterns. Agri Econ Rese Revi. 2016;29(conf):31. doi:10.5958/0974-0279.2016.00031.8
36. Raji A, Seely EW, Arky RA, Simonson DC. Body fat distribution and insulin resistance in healthy Asian Indians and Caucasians. J Clin Endocrinol Metab. 2001;86(11):5366-5371. doi:10.1210/jcem.86.11.7992
37. Right to Protein, Madan J. Indias-Protein-Paradox-Study.pdf. Accessed November 10, 2022. https://righttoprotein.com/assets/pdf/Indias-Protein-Paradox-Study.pdf
38. Hoffman JR, Falvo MJ. Protein – Which is Best? J Sports Sci Med. 2004;3(3):118-130.
39. Nisak MB, Ruzita AT, Norimah AK, Azmi KN, Fatimah A. Acute Effect of Low and High Glycemic Index Meals on Post-prandial Glycemia and Insulin Responses with Type 2 Diabetes Mellitus. Malaysian Journal of Medicine and Health Sciences. 2009;5(1):11-20. Accessed March 17, 2022. http://wprim.whocc.org.cn/admin/article/articleDetail?WPRIMID=628073&articleId=628073
40. Vlachos D, Malisova S, Lindberg FA, Karaniki G. Glycemic Index (GI) or Glycemic Load (GL) and Dietary Interventions for Optimizing Postprandial Hyperglycemia in Patients with T2 Diabetes: A Review. Nutrients. 2020;12(6). doi:10.3390/nu12061561