Abstract
Background: Food products with a low Glycemic index (GI) and low Glycemic load (GL) help control blood glucose levels, and reduce the risk of diabetes-related morbidity and mortality. Vidavance®, an oral nutritional supplement (ONS) and Medical Nutrition Therapy (MNT) for pre-diabetes and diabetes has high-quality protein blend (soy protein isolate, calcium caseinate), dietary fiber (polydextrose, soy fiber), modified maltodextrin, chromium, and zinc, which are known to influence blood glucose control.
Aim: To determine the GI and GL of the Vidavance® in 31 people with diabetes (T2DM) aged 18 to 60 years, with fasting blood glucose (FBG) >120 mg / dL.
Methodology: The study participants consumed reference food (27.5 g of glucose monohydrate dissolved in 125 ml of water) followed by a three-day washout period. Then Vidavance® test dose (53 g available carbohydrate/100 gm) was given as 47.1.g of ONS mixed in 100 ml water to make up 390 ml). Continuous Glucose Monitoring reading was taken at 0, 15, 30, 45, 60, 90, and 120 minutes after the start of the test meal. The GI was assessed using a validated protocol by FAO and ISO (2010).
Results: 30 participants completed the study, (Mean age 55.2 ± 13.0 years.). The GI of the test food (Vidavance®) was 30.57 (low GI). No hyperglycemic events were observed during the study. The GI value was not influenced by age (years), sex, previous day’s dietary intake energy (kcal), and physical activity level. The GL of the test food was 3.85 (low GL).
Conclusion: Vidavance® is a low GI and low GL ONS and hence suitable for diabetic subjects.