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01 · ABSTRACT

Abstract

Estrogen, a powerful hormone, is intricately linked to breast cancer susceptibility. This review navigates the intricate web of connections between dietary and environmental estrogen exposures and the development of breast cancer. We meticulously explore diverse sources, ranging from natural plant-derived estrogens like soy isoflavones to pervasive environmental contaminants such as bisphenol A, scrutinizing their potential impact on cancer risk. Our inquiry delves into the intricate molecular mechanisms through which these exposures interact with estrogen receptors, igniting downstream signaling pathways that fuel breast cell proliferation and survival. While conventional risk assessment tools provide valuable insights, we also shed light on modifiable lifestyle factors individuals can embrace to potentially mitigate their risk, advocating for the maintenance of a healthy weight and regular physical activity. Yet, amidst the scientific inquiry, we acknowledge the ongoing debates and limitations, particularly concerning the robustness of associations between specific exposures and cancer risk. Ultimately, we champion the dissemination of evidence-based knowledge, empowering individuals to make informed decisions about their dietary choices, lifestyle modifications, and potential interventions, thereby fostering a future where individuals possess the agency to proactively manage their breast cancer risk profile.

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02 · PUBLICATION RECORD

Article details

JournalMedical Research Archives
IssueVol 12 No 6 (2024): Vol 12 No 6 (2024): JUNE issue, Issue 6, VOl.12
SectionResearch Articles
Published24 June 2024
DOI10.18103/mra.v12i6.5461
ISSN2375-1924
03 · RIGHTS & REUSE

Rights & reuse

This article is published under a Creative Commons Attribution License (CC BY 3.0) and may be shared or distributed by anyone as long as attribution is given to the journal.

Authors & affiliations

SR

S. Ravichandran

Professor in Chemistry, School of Mechanical Engineering, Lovely Professional University, Jalandhar- 144 411, Punjab, India.

ZS

Zeliha Selamoglu

Department of Medical Biology, Medicine Faculty, Nigde Omer Halisdemir University, Nigde, Türkiye. Western Caspian University, Baku, Azerbaijan. Khoja Akhmet Yassawi International Kazakh-Turkish University, Faculty of Sciences, Department of Biology, Central Campus, Turkestan, Kazakhstan.

MN

Muhammad Yasir Naeem

Department of Plant Production and Technologies, Faculty of Agricultural Sciences and Technologies, Nigde Omer Halisdemir University, Nigde, Türkey.

EA

Elifsena Canan Alp Arici

Department of Obstetrics and Gynecology, Faculty of Medicine, Necmettin Erbakan, University of Meram, Konya, Türkey.

MN

Muhammad Raza Naqvi

Medical Director (Hematologist/Oncologist) and Cancer Liason Physician Inter mountain Health Care, Denver, USA.

RS

R. M. Madhumitha Sri

Associate Analyst, Zifo Technologies Pvt. Ltd., Manapakkam, Chennai-600 089 (Tamilnadu) India.

AC

Aarushi Chhibber

Department of Biotechnology, School of Bio Engineering and Bio sciences, Lovely Professional University, Jalandhar-144411, Punjab, India.

KR

Karthika P. R.

Student, B.Tech. Aerospace Engineering, School of Mechanical Engineering, Lovely Professional University, Jalandhar-144 411 (Punjab)

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