The Unusual Sequence of Lymphomatoid Papulosis Following Hodgkin's Disease: A Case Report

Main Article Content

Dr. Linu Abraham Jacob Dr Dayanand Sagar P Dr. Animesh Gupta Dr Priya D Dr. M C Suresh Babu Dr. Lokesh K N Dr. A H Rudresha Dr. Rajeev L K Dr. Smitha C Saldanha

Abstract

Lymphomatoid papulosis (LyP) is a rare skin disease which is characterised by chronic, recurrent self-healing papulo-nodular skin lesions. It is classified under the group of primary cutaneousCD30+ve lymphoproliferative disorders. It is important to diagnose LyP as it is usually associated with other malignant lymhoproliferative disorders like mycosis fungoides, cutaneous or systemic anaplastic large cell lymphoma and Hodgkin's lymphoma. LyP associated malignancies may occur before, concurrent with or after the onset of LyP. In most of the cases previously described, Hodgkin's disease has developed after, or concurrently with, the onset of LyP. Here we report a case of LyP that developed 5 years after the onset and therapy for Hodgkin's lymphoma.

Keywords: Lymphomatoid papulosis, Hodgkins lymphoma, papulonodular

Article Details

How to Cite
JACOB, Dr. Linu Abraham et al. The Unusual Sequence of Lymphomatoid Papulosis Following Hodgkin's Disease: A Case Report. Medical Research Archives, [S.l.], v. 12, n. 6, june 2024. ISSN 2375-1924. Available at: <https://esmed.org/MRA/mra/article/view/5498>. Date accessed: 22 july 2024. doi: https://doi.org/10.18103/mra.v12i6.5498.
Section
Case Reports

References

1. Verma D, Lakhani R, Mendiratta V, Chatterjee P. Lymphomatoid Papulosis: A Case Report. Indian Dermatol Online J. 2023;15(1):95-98. Published 2023 Nov 24. Doi: 10.4103/idoj.idoj_194_23
2. Chen KTK, Flam MS. Hodgkinʼs disease complicating lymphomatoid papulosis. Am J Dermatopathol. 1985;7(6):555-562. Doi:10.1097/00000372-198512000-00010
3. Pinto GM, Gonçalves L, Gonçalves H, et al. A case of lymphomatoid papulosis and Hodgkin’s disease. J Am Acad Dermatol. 1989;21(5):1051-1056. Doi:10.1016/s0190-9622(89)70294-2
4. Macaulay WL. Lymphomatoid papulosis. A continuing self-healing eruption, clinically benign--histologically malignant. Arch Dermatol. 1968;97(1):23-30. Doi:10.1001/archderm.97.1.23
5. Willemze R, Meijer CJLM. Primary cutaneous CD30-positive lymphoproliferative disorders. Hematol Oncol Clin North Am. 2003;17(6):1319-1332. Doi:10.1016/s0889-8588(03)00117-5
6. Willemze R, Cerroni L, Kempf W, et al. The 2018 update of the WHO-EORTC classification for primary cutaneous lymphomas. Blood. 2019;133(16):1703-1714. Doi:10.1182/blood-2018-11-881268
7. Willemze R, Scheffer E, Van Vloten WA, Meijer CJLM. Lymphomatoid papulosis and Hodgkin’s disease: Are they related? Arch Derm Res. 1983;275(3):159-167. Doi:10.1007/bf00510047
8. Hakkou D, Belefqih I, Sabri S, et al. Primary cutaneous hodgkin’s lymphoma: An extremely rare entity. Cureus. Published online 2021. Doi:10.7759/cureus.19272
9. Kadin ME. Lymphomatoid papulosis, Ki-1+ lymphoma, and primary cutaneous Hodgkin's disease. Semin Dermatol. 1991;10(3):164-171.
10. Scheen SR III, Doyle JA, Winkelmann RK. Lymphoma-associated papulosis: Lymphomatoid papulosis associated with lymphoma. J Am Acad Dermatol. 1981;4(4):451-457. Doi:10.1016/s0190-9622(81)70046-x
11. Sanchez NP, Pittelkow MR, Muller SA, Banks PM, Winkelmann RK. The clinicopathologic spectrum of lymphomatoid papulosis: Study of 31 cases. J Am Acad Dermatol. 1983;8(1):81-94. Doi:10.1016/s0190-9622(83)70011-3
12. Lederman JS, Sober AJ, Harrist TJ, Lederman GS. Lymphomatoid papulosis following Hodgkin’s disease. J Am Acad Dermatol. 1987;16(2):331-335. Doi:10.1016/s0190-9622(87)70045-0
13. Kempf W, Pfaltz K, Vermeer MH, et al. EORTC, ISCL, and USCLC consensus recommendations for the treatment of primary cutaneous CD30-positive lymphoproliferative disorders: lymphomatoid papulosis and primary cutaneous anaplastic large-cell lymphoma. Blood. 2011;118(15):4024-4035. Doi:10.1182/blood-2011-05-351346
14. Wantzin GL, Thomsen K. Methotrexate in lymphomatoid papulosis. Br J Dermatol. 1984;111(1):93-95. Doi:10.1111/j.1365-2133.1984.tb04021.x
15. Davis TH, Morton CC, Miller-Cassman R, Balk SP, Kadin ME. Hodgkin’s disease, lymphomatoid papulosis, and cutaneous T-cell lymphoma derived from a common T-cell clone. N Engl J Med. 1992;326(17):1115-1122. Doi:10.1056/nejm199204233261704