Abstract
Oral health-related quality of life plays a crucial role in dental practice. Numerous systemic factors, including inadequate nutrition, tobacco use, stress, medication consumption, and diabetes, among others, have been demonstrated to affect oral health. Specific systemic treatments, such as chemo-radiotherapy for head and neck malignancies, cardiac valve replacement, bisphosphonate therapy, and allogeneic hematopoietic stem cell transplantation (HSCT), can impact oral health both during and after the primary treatment. Providing dental care for medically compromised individuals can be complex, particularly with regard to dental procedures and urgent care. An essential aspect of healthcare involves modifying dental treatments for patients whose medical conditions necessitate alterations. For these patients, dental examinations and clearances offer opportunities to deliver comprehensive preventive care that transcends professional boundaries. These consultations also provide occasions to propose treatment options before, during, and after dental visits. While numerous research studies have explored this topic, dental practitioners have not widely adopted it due to limited understanding of medical conditions. Given these clinical challenges, it is imperative to address and elucidate the dental clearance issue for common medical conditions frequently encountered in dental practice. Furthermore, there is a necessity to establish clinical protocols for assessment and management prior to medical procedures.