Abstract
This paper seeks to provide a comprehensive review of the utilization of placental tissue therapies in addressing the challenges posed by diabetic foot ulcers (DFUs). A systematic review approach was employed, utilizing the PubMed database to identify relevant research papers. Following the initial search, a rigorous screening process was undertaken, comprising two rounds of screening to ensure the inclusion of relevant studies. The review showed that placental tissue therapies are effective for diabetic foot ulcers (DFUs). They can be applied topically, injected, or implanted, leading to faster wound healing and tissue regeneration. Studies found quicker closure of wounds, shorter healing times, and better outcomes with these treatments. Placental tissues contain mesenchymal stem cells and growth factors, making them effective for diabetic foot ulcers management. They offer a promising way to speed up wound healing and enhance patient outcomes. Further research is warranted to validate these findings and explore optimal treatment protocols for maximizing the therapeutic benefits of placental tissue therapies in diabetic foot ulcers management.