Clinical results and histopathological findings of laparoscopic sleeve gastrectomy specimens

Article Sidebar

PDF
Published Mar 29, 2025
DOI: https://doi.org/10.18103/mra.v3i3.6362

Downloads

Download data is not yet available.

Submit your own article

Register as an author to reserve your spot in the next issue of the Medical Research Archives.

Author Registration

Join the Society

The European Society of Medicine is more than a professional association. We are a community. Our members work in countries across the globe, yet are united by a common goal: to promote health and health equity, around the world.

Join Europe’s leading medical society and discover the many advantages of membership, including free article publication.

Membership

Main Article Content

Hayder Makki Al-Masari, MD
Emirates Health Services
Maryam Salem Alkhatry, MD
Emirates Health Services
Abdulwahid Alwahedi, MD
Emirates Health Services
Dana Othman, MD
Emirates Health Services
Rahaf Abughosh, MD
Emirates Health Services

Abstract

Background and objectives: The opportunity of evaluating histological changes has increased since laparoscopic sleeve gastrectomy (LSG) has been a common surgical treatment for morbid obesity in recent years. This research was designed to describe gastric specimens that has been surgically resected.


The study was conducted retrospectively based on records from a single center in the UAE.


Results: Of 585 patients, 205 were men (35%) and 380 were women (65%). The average body mass index was 43.8 kg/m2. The average age at the time of the operation was 29.93 years. 202 patients (34.5%), had histopathologic findings in the resected specimens. The main histopathologic findings were normal stomach mucosa (383, or 65.5%) and chronic gastritis was the second most common diagnosis, with 182 cases (31.2%), followed by H pylori positivity in 11 samples (1.3%) and Dysplasia-intestinal metaplasia was found in 5 patients (0.9%) of the patients. Out of those with chronic gastritis it was found that 51 (28%) cases had positive H pylori test earlier.


Conclusions: All sleeve gastrectomy specimens should be histologically examined, as the results revealed curable problems where endoscopies prior to sleeve gastrectomy may have missed some lesions, histopathologic investigations are crucial for accurate diagnosis.


Several variables, including age, gender, the histology of the stomach that was removed, and the presence or absence of H. pylori, should be taken into account when attempting to predict the success of weight loss following surgery.

Keywords: Sleeve Gastrectomy, histopathology, gastritis, H pylori

Article Details

How to Cite
AL-MASARI, Hayder Makki et al. Clinical results and histopathological findings of laparoscopic sleeve gastrectomy specimens. Medical Research Archives, [S.l.], v. 13, n. 3, mar. 2025. ISSN 2375-1924. Available at: <https://esmed.org/MRA/mra/article/view/6362>. Date accessed: 06 apr. 2025. doi: https://doi.org/10.18103/mra.v3i3.6362.
ABNT APA BibTeX CBE EndNote - EndNote format (Macintosh & Windows) MLA ProCite - RIS format (Macintosh & Windows) RefWorks Reference Manager - RIS format (Windows only) Turabian
Issue
Vol 13 No 3 (2025): Vol.13, Issue 3, March 2025
Section
Research Articles

The Medical Research Archives grants authors the right to publish and reproduce the unrevised contribution in whole or in part at any time and in any form for any scholarly non-commercial purpose with the condition that all publications of the contribution include a full citation to the journal as published by the Medical Research Archives.

 

References

1. World Health Organization. Obesity and overweight. Published December 9, 2023. Accessed February 24, 2025. https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight.
2. Solomon CG, Dluhy RG. Bariatric surgery—quick fix or long-term solution? N Engl J Med. 2004;351(26):2751-2753.
3. Sjöström L, Lindroos AK, Peltonen M, et al. Lifestyle, diabetes, and cardiovascular risk factors 10 years after bariatric surgery. N Engl J Med. 2004;351(26):2683-2693.
4. Buchwald H, Oien DM. Metabolic/bariatric surgery worldwide 2008. Obes Surg. 2009;19(12):1605-1611.
5. Onzi TR, d’Acampora AJ, de Araújo FM, et al. Gastric histopathology in laparoscopic sleeve gastrectomy: Pre- and post-operative comparison. Obes Surg. 2014;24(3):371-376.
6. Ge L, Moon RC, Nguyen H, de Quadros LG, Teixeira AF, Jawad MA. Pathologic findings of the removed stomach during sleeve gastrectomy. Surg Endosc. 2019;15(1):1-5.
7. Vrabie CD, Cojocaru M, Waller M, Sindelaru R, Copaescu C. The main histopathological gastric lesions in obese patients who underwent sleeve gastrectomy. Dicle Med J. 2010;37(2):1.
8. Schirmer B, Schauer PR. The surgical management of obesity. In: Brunicardi F, Andersen D, Hunter J, et al., eds. Schwartz’s Principles of Surgery. 10th ed. McGraw-Hill; 2016:952-953.
9. Ohanessian SE, Rogers AM, Karamchandani DM. Spectrum of gastric histopathologies in severely obese American patients undergoing sleeve gastrectomy. Obes Surg. 2016;26(3):595-602.
10. AbdullGaffar B, Raman L, Khamas A, AlBadri F. Should we abandon routine microscopic examination in bariatric sleeve gastrectomy specimens? Obes Surg. 2016;26(1):105-110.
11. Clapp B. Histopathologic findings in the resected specimen of a sleeve gastrectomy. JSLS. 2015;19(1):e2013.00259.
12. Raess PW, Baird-Howell M, Aggarwal R, Williams NN, Furth EE. Vertical sleeve gastrectomy specimens have a high prevalence of unexpected histopathologic findings requiring additional clinical management. Surg Obes Relat Dis. 2015;11(5):1020-1023.
13. Almazeedi S, Al-Sabah S, Al-Mulla A, et al. Gastric histopathologies in patients undergoing laparoscopic sleeve gastrectomies. Obes Surg. 2013;23(3):314-319.
14. Lauti M, Gormack SE, Thomas JM, Morrow JJ, Rahman H, MacCormick AD. What does the excised stomach from sleeve gastrectomy tell us? Obes Surg. 2016;26(4):839-842.
15. Safaan T, Bashah M, El Ansari W, Karam M. Histopathological changes in laparoscopic sleeve gastrectomy specimens: Prevalence, risk factors, and value of routine histopathologic examination. Obes Surg. 2017;27(7):1741-1749.
16. Yamamoto S, Watabe K, Takehara T. Is obesity a new risk factor for gastritis? Digestion. 2012;85(2):108-110.
17. Erkinuresin T, Demirci H, Cayci HM, Erdogdu UE. The relationship between histopathologic findings and weight loss in laparoscopic sleeve gastrectomy. Obes Surg. 2020;30(2):478-482.
18. Suerbaum S, Michetti P. Helicobacter pylori infection. N Engl J Med. 2002;347(15):1175-1186.
19. Khedmat H, Karbasi-Afshar R, Agah S, Taheri S. Helicobacter pylori infection in the general population: A Middle Eastern perspective. Casp J Intern Med. 2013;4(4):745-753.
20. Eshraghian A. Epidemiology of Helicobacter pylori infection among the healthy population in Iran and countries of the Eastern Mediterranean Region: A systematic review of prevalence and risk factors. World J Gastroenterol. 2014;20(46):17618-17625.
21. Khalilpour A, Kazemzadeh-Narbat M, Tamayol A, Oklu R, Khademhosseini A. Biomarkers and diagnostic tools for detection of Helicobacter pylori. Appl Microbiol Biotechnol. 2016;100(11):4723-4734.
22. Albawardi A, Almarzooqi S, Torab FC. Helicobacter pylori in sleeve gastrectomies: Prevalence and rate of complications. Int J Clin Exp Med. 2013;6(2):140-143.
23. Carabotti M, D’Ercole C, Iossa A, Corazziari E, Silecchia G, Severi C. Helicobacter pylori infection in obesity and its clinical outcome after bariatric surgery. World J Gastroenterol. 2014;20(3):647-653.
24. Leung WK, Ng EKW, Chan WY, Auyeung ACM, Chan KF, Lam CCH, et al. Risk factors associated with the development of intestinal metaplasia in first-degree relatives of gastric cancer patients. Cancer Epidemiol Biomark Prev. 2005;14(12):2982-2986.
25. Chen XY, Liu WZ, Shi Y, Zhang DZ, Xiao SD, Tytgat GNJ. Helicobacter pylori-associated gastric diseases and lymphoid tissue hyperplasia in gastric antral mucosa. J Clin Pathol. 2002;55(2):133-137.