Ozone Therapy – An Unmatched Approach for Near Universal Prevention and Treatment

Abstract

Ozone therapy (OT) has been published for decades as a versatile therapy for a wide variety of conditions. The purpose of this report is to bring forward known biochemistry which supports clinical observations of its utility.

Extraordinarily safe, ozone can be administered locally or systemically, or both, to any part of the body except lungs. OT improves oxygen delivery and uptake by a variety of mechanisms. It safely modulates inflammation by reducing inflammatory enzymes and raising and raising anti-inflammatory cytokines and mediators. OT activates the critical Nrf2 transcription pathway, which functions include crucial anti-oxidant enzymes production, DNA repair, mitochondrial protection and biogenesis, protein folding, anti-ageing, and more. OT preconditioning protects the organism against chemical and infection stressors, and reperfusion injury. It has adjunct uses in the management of cancer, and may slow ageing processes and degenerative disease, particularly skeletal by local injection. OT has significant utility in dentistry for prevention, treatment, repair and regeneration, including articular cartilage. Because ozone is not patentable for profit, and would clearly challenge the current medical paradigm of disease maintenance drug therapy, it remains a “pariah” to drug promoting regulatory authorities, while it could address the urgent universal need for safe, effective, and non-resistance promoting approaches to infectious diseases and “superbugs”, including generally untreatable viral disease. OT suffers from the “tomato effect” in that mainstream medicine shuns it, even where conventional medicine has dangerous approaches or no answers at all.