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01 · ABSTRACT

Abstract

Introduction and Importance: Dermal fillers are pivotal in aesthetic enhancement, offering minimally invasive solutions for facial rejuvenation. This case underscores the stark contrast in appearance following elective hyaluronidase dissolution of long-term fillers and examines the challenges of transitioning to fat transfer as an alternative.

Presentation of Case: A 50+ year-old Asian female, with a history of dermal fillers over 10 years, sought hyaluronidase dissolution to facilitate fat transfer. The dramatic aging effects post-dissolution left the patient deeply dissatisfied. Subsequent fat transfer in another country failed to meet aesthetic expectations, despite undergoing 2 sessions.

Clinical Discussion: This report highlights the transformative benefits of dermal fillers, the risks associated with high-dose hyaluronidase, and the complexities of achieving comparable outcomes with fat transfer.

Conclusion: Properly placed fillers provide profound aesthetic benefits. The case underscores the importance of careful evaluation before administration of hyaluronidase.

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02 · PUBLICATION RECORD

Article details

JournalMedical Research Archives
IssueVol 13 No 6 (2025): Vol.13, Issue 6, June 2025
SectionCase Reports
Published29 June 2025
DOI10.18103/mra.v13i6.6650
ISSN2375-1924
03 · RIGHTS & REUSE

Rights & reuse

This article is published under a Creative Commons Attribution License (CC BY 3.0) and may be shared or distributed by anyone as long as attribution is given to the journal.

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