Diminished distal dorsal finger crease is associated with handgrip weakness in inclusion body myositis

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Published Jul 31, 2025
DOI: https://doi.org/10.18103/mra.v13i7.6773

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Main Article Content

Matthew K Preston, MD
Department of Neurology, University of Washington, Seattle, Washington. University of Washington Medical Center, Box 356465, 1959 NE Pacific Street. Seattle, WA 98195-6465
Ava Yun Lin, MD, PhD
Department of Pediatrics, University of Michigan
Kevin Dooley, MD
Cure IBM, Davis, CA
Conrad C Weihl, MD, PhD
Department of Neurology, Washington University in St. Louis
Leo H Wang, MD, PhD
Department of Neurology, University of Washington, Seattle, Washington. University of Washington Medical Center, Box 356465, 1959 NE Pacific Street. Seattle, WA 98195-6465

Abstract

Background: Sporadic inclusion body myositis is a common cause of myopathy in populations over age 45 which classically causes distal finger flexor weakness. Loss of distal dorsal finger creases has been previously noticed in this disease.


Aims: Investigate the association between distal finger creases and grip strength in patients with inclusion body myositis.


Methods: We studied the crease pattern of the dorsal distal interphalangeal joints as well as handgrip strength in 81 affected and 74 control patients.


Results: A subset of patients with inclusion body myositis who had loss of crease of the dorsal fingers had weaker handgrip strength.


Conclusions: The loss of creases of the dorsal fingers is an additional complementary physical exam finding to identify inclusion body myositis and is associated with grip weakness.

Article Details

How to Cite
PRESTON, Matthew K et al. Diminished distal dorsal finger crease is associated with handgrip weakness in inclusion body myositis. Medical Research Archives, [S.l.], v. 13, n. 7, july 2025. ISSN 2375-1924. Available at: <https://esmed.org/MRA/mra/article/view/6773>. Date accessed: 14 dec. 2025. doi: https://doi.org/10.18103/mra.v13i7.6773.
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Issue
Vol 13 No 7 (2025): Vol.13, Issue 7, July 2025
Section
Research Articles

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