Anterior Cruciate Ligament Ganglion Cyst: Uncommon Cause of Knee Pain

Main Article Content

José María Busto Villarreal http://orcid.org/0000-0002-2094-1954 Jimena Guadalupe Prado Peláez http://orcid.org/0000-0002-3129-2865 Aldo Vázquez Godínez http://orcid.org/0000-0001-9800-0663 Juan Felipe Gómez Castillo http://orcid.org/0009-0001-6198-036X

Abstract

Purpose: Anterior cruciate ligament (ACL) ganglion cysts are rare intra-articular lesions, particularly uncommon in the pediatric population. This report describes a symptomatic ACL ganglion in a child, detailing clinical presentation, imaging findings, arthroscopic management, and postoperative outcome, and reviews the current literature.


Methods: We present the case of a 7-year-old male with a 3-month history of progressive right knee pain, culminating in extension block. Clinical examination revealed a 10° extension deficit without instability or swelling. Magnetic resonance imaging (MRI) demonstrated an intrasubstance ganglion cyst within the proximal and middle thirds of the ACL, associated with partial fiber disruption. Arthroscopic resection and aspiration of the cyst were performed, followed by a structured rehabilitation program.


Results: Arthroscopy confirmed a ganglionic lesion attached to the ACL walls, with intact menisci and no other intra-articular pathology. Complete cyst excision was achieved without complications. At 3-month follow-up, the patient was pain-free, had regained full range of motion and strength, and returned to sports activities.


Conclusion: Although rare in children, ACL ganglion cysts should be considered in the differential diagnosis of pediatric knee pain with unexplained motion restriction. MRI is the diagnostic modality of choice, and arthroscopic resection offers an effective and definitive treatment with excellent functional recovery.

Keywords: anterior cruciate ligament, ganglion cyst, knee, arthroscopy, pediatric orthopedics

Article Details

How to Cite
BUSTO VILLARREAL, José María et al. Anterior Cruciate Ligament Ganglion Cyst: Uncommon Cause of Knee Pain. Medical Research Archives, [S.l.], v. 13, n. 9, sep. 2025. ISSN 2375-1924. Available at: <https://esmed.org/MRA/mra/article/view/6924>. Date accessed: 06 dec. 2025. doi: https://doi.org/10.18103/mra.v13i9.6924.
Section
Case Reports

References

1. Zampeli F, Terzidis I, Bernard M, Ochi M, Anastasios G. The Anterior Cruciate Ligament: Reconstruction and Basic Science. 2nd ed. 2018:431–436.

2. Casas-Duhrkop D, Ares O, Seijas R, Cugat RJ. Ganglión en ligamento cruzado anterior: a propósito de un caso. Acta Ortop Mex. 2013;27(4):246–249.

3. Fillingham YA, Coe MP, Hellman M, Haughom B, Adeniran AO, Sparks MB. Report of ganglion cyst in the anterior cruciate ligament of a 6-year-old child. Knee. 2013;20(2):144–147. doi:10.1016/j.knee.2012.10.008

4. Mao Y, Dong Q, Wang Y. Ganglion cysts of the cruciate ligaments: A series of 31 cases and review of the literature. BMC Musculoskelet Disord. 2012;13:2–5.

5. Sonnery-Cottet B, et al. Anterior Cruciate Ligament Ganglion Cyst Treated Under Computed Tomography–Guided Aspiration in a Professional Soccer Player. Orthop J Sports Med. 2016;4(5). doi:10.1177/2325967116644585

6. Vaishya R, Issa AE, Agarwal AK, Vijay V. Anterior Cruciate Ligament Ganglion Cyst and Mucoid Degeneration: A Review. Cureus. 2017;9(9):e1682. doi:10.7759/cureus.1682

7. Pimprikar MV, Patil HG. Anterior Cruciate Ligament Ganglion and Decompression of Mucoid Degeneration Using a “Figure-of-4 Position.” Arthrosc Tech. 2024;13(8):103026. doi:10.1016/j.eats.2024.103026

8. Krill M, Peck E. Percutaneous Ultrasound-Guided Aspiration of an Anterior Cruciate Ligament Ganglion Cyst: Description of Technique and Case Presentation. PM&R. 2014;6(12):1166–1169. doi:10.1016/j.pmrj.2014.07.008

9. Demircay E, Ofluoglu D, Ozel O, Oztop P. Simultaneous bilateral ganglion cysts of the anterior cruciate ligaments. Singapore Med J. 2015;56(4):e59–e61. doi:10.11622/smedj.2015062

10. Lunhao B, Yu S, Jiashi W. Diagnosis and treatment of ganglion cysts of the cruciate ligaments. Arch Orthop Trauma Surg. 2011;131(8):1053–1057. doi:10.1007/s00402-011-1286-5

11. Kang CN, Lee SB, Kim SW. Symptomatic ganglion cyst within the substance of the anterior cruciate ligament. Arthroscopy. 1995;11(5):612–615. doi:10.1016/0749-8063(95)90141-8

12. Andrikoula SI, Vasiliadis HS, Tokis AV, Kosta P, Batistatou A, Georgoulis AD. Intra-articular ganglia of the knee joint associated with the anterior cruciate ligament: a report of 4 cases in 3 patients. Arthroscopy. 2007;23(7):800.e1–6. doi:10.1016/j.arthro.2006.05.032