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01 · ABSTRACT

Abstract

Magnetic resonance urography (MRU) has evolved over the past three decades into a validated tool for evaluating the pediatric urinary tract. Originally developed in the early 1990s, MRU now combines high-resolution anatomic imaging with quantitative functional assessment, offering a radiation-free alternative to traditional modalities. Comparative studies have consistently demonstrated excellent agreement between MRU-derived differential renal function and radionuclide scintigraphy. Beyond functional equivalence, MRU provides superior delineation of complex anomalies such as megaureter and ectopic ureteral insertion, directly informing surgical planning. Recent innovations have enhanced feasibility in younger children, with real-time imaging and compressed sensing reducing scan times by 30–50% and improving motion robustness. Multiparametric protocols integrating diffusion and perfusion sequences, as well as emerging multi-nuclear approaches, extend MRU’s role into parenchymal and physiologic evaluation. Collectively, these advances shift MRU from a problem-solving adjunct to a central modality in pediatric urology, with future directions focused on standardization, multicenter validation, and potential integration of artificial intelligence for quantitative analysis.

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02 · PUBLICATION RECORD

Article details

JournalMedical Research Archives
IssueVol 13 No 10 (2025): Vol.13, Issue 10, October 2025
SectionReview Articles
Published28 October 2025
DOI10.18103/mra.v13i10.6990
ISSN2375-1924
03 · RIGHTS & REUSE

Rights & reuse

This article is published under a Creative Commons Attribution License (CC BY 3.0) and may be shared or distributed by anyone as long as attribution is given to the journal.

Authors & affiliations

BP

Benjamin Press

Pediatric Urology Department, Emory University School of Medicine, Pediatric Urology Department, Children's Healthcare of Atlanta

AK

Andrew Kirsch, MD, FAAP

Pediatric Urology Department, Emory University School of Medicine, Pediatric Urology Department, Children's Healthcare of Atlanta & Pediatric Urology Department, Georgia Urology.

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