Abstract
With the recent focus on diagnosis and treatment in the United States of chronic illness stemming from exposure to the interior of water-damaged buildings, there has been greater use of unsupported laboratory testing. Prior extensive published studies have provided rigorous support for the causation of illness called Chronic Inflammatory Response Syndrome (CIRS). Still, we have not yet seen any studies of exposure to mycotoxins alone that have withstood peer review. The absence of control groups, prospective case-control studies, and placebo-controlled studies makes conclusions of causation impossible. In contrast, such basic studies are well represented in the peer-reviewed literature on CIRS.