Staphylococcal Scalded Skin Syndrome in an Elderly Patient: A Rare and Life-Threatening Presentation

Abstract

Staphylococcal scalded skin syndrome (SSSS) is a toxin-mediated exfoliative dermatosis caused by Staphylococcus aureus, typically affecting neonates and young children. Adult cases are rare but associated with high mortality, particularly in elderly and immunocompromised patients [1,2].
We describe an 85-year-old woman admitted with sepsis secondary to a urinary tract infection who subsequently developed diffuse erythema, superficial desquamation, and a positive Nikolsky sign. Histopathological findings were compatible with SSSS. Prompt antimicrobial therapy and supportive care resulted in complete clinical recovery.
This case underscores the importance of early recognition of SSSS in adults, differentiation from Stevens-Johnson syndrome, and timely initiation of appropriate therapy to reduce morbidity and mortality.