01 · ABSTRACT
Abstract
Metabolic syndrome is epigenetically related to mood disorders. Seasonality is a predictor of metabolic syndrome. Obesity is more common in the West than in the East. This is not solely due to industrialized societies. It should be emphasized that the frequency of major depressive disorder increases as one moves north. However, seasonal affective disorder is intermeridian. Mood is also closely related to how we perceive and experience nature. Different time scales between the organism/body-brain and the world synchronize to serve the minimization of free energy. Spatial-temporal dynamics, referred to as a common currency, serve adaptation. Autism and affective spectrum disorder are spatiotemporal pathologies. In depression, internal time is slow, external time is fast. The opposite is true in mania. The loss of the connection between internal and external time, which is crucial for perception and memory, explains how the sense of self can be lost in psychosis.
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Keywords
Mood disordersAffective spectrumMetabolic syndromeNeuroecologyEpigeneticsHomo spatiotemporalis
03 · PUBLICATION RECORD
Article details
JournalMedical Research Archives
IssueVol 14 No 3 (2026): Vol.14, Issue 3, March 2026
SectionEditorial
Published01 April 2026
DOI10.18103/mra.v14i3.7326
ISSN2375-1924
04 · RIGHTS & REUSE
Rights & reuse
This article is published under a Creative Commons Attribution License (CC BY 3.0) and may be shared or distributed by anyone as long as attribution is given to the journal.