Integrated Approaches to Dengue Prevention: Vector Control and Vaccine Performance, , and Future Directions
Main Article Content
Abstract
Abstract
Dengue fever is a global health threat driven by climate change, rapid urbanization, and the expanding distribution of Aedes mosquitoes. With an estimated 100 - 400million infections annually. Dengue poses significant challenges for clinical management and public health preparedness because of the need to act on the four viral serotypes causing the infection Emphasis is placed on vector control strategies and the development and licensing of dengue vaccines, including Dengvaxia (CYD-TDV) and Qdenga (TAK-003), with analysis of their design, mechanisms, safety profiles, and serostatus-dependent performance highlighting the immunological and operational challenges that continue to complicate dengue vaccination.
The review outlines the future priorities, such as next-generation vaccine development, improved surveillance systems, and scalable vector-control innovations, underscoring the need for integrated, evidence-based strategies to reduce dengue transmission and the global disease burden.
Dengue fever is a global health threat driven by climate change, rapid urbanization, and the expanding distribution of Aedes mosquitoes. With an estimated 100 - 400million infections annually. Dengue poses significant challenges for clinical management and public health preparedness because of the need to act on the four viral serotypes causing the infection Emphasis is placed on vector control strategies and the development and licensing of dengue vaccines, including Dengvaxia (CYD-TDV) and Qdenga (TAK-003), with analysis of their design, mechanisms, safety profiles, and serostatus-dependent performance highlighting the immunological and operational challenges that continue to complicate dengue vaccination.
The review outlines the future priorities, such as next-generation vaccine development, improved surveillance systems, and scalable vector-control innovations, underscoring the need for integrated, evidence-based strategies to reduce dengue transmission and the global disease burden.
Article Details
How to Cite
A FERNANDEZ C, EDUARDO; MUDASSAR, Maryam.
Integrated Approaches to Dengue Prevention: Vector Control and Vaccine Performance, , and Future Directions.
Medical Research Archives, [S.l.], v. 14, n. 4, may 2026.
ISSN 2375-1924.
Available at: <https://esmed.org/MRA/mra/article/view/7446>. Date accessed: 01 may 2026.
Keywords
Dengue, severe dengue, mosquito control, vaccine development, licensing
Section
Review Articles
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