Localized Amyloidosis of the Breast Mimicking Breast Cancer: Radiologic-Pathologic Correlation

Amyloidosis localized to the breast is uncommon. It may present with nonspecific imaging characteristics including a suspicious mass with or without calcifications, calcifications alone, or even with features mimicking inflammatory carcinoma of the breast. Amyloidosis has also been described coexistent with primary carcinoma of the breast, further confounding the imaging spectrum. We describe a case of amyloidosis localized to the breast presenting as a new mass with imaging features highly suggestive of malignancy.