Bladder cancer in patients under 40 years. A French experience and a review of the recent literature.

Abstract

Introduction

Bladder cancer is a disease of people around the 60ies. Hhere we describe a large series of bladder cancers in patients under 40 years. Only patients treated in france were taken into consideration

Materials and Methods

This retrospective study includes 156 patients treated between 1992 and 2013 with less than 40 years at the time of diagnosis. Tumours were classified according to the 8^th TNM edition and WHO 2016 edition.

Results

156 patients were included. Hundred fourty-four were urolthelial carcinomas, 12 had other patterns. PUNLMP was a frequent finding (28%), 128 had non muscle invasive tumours. Fourteen patients displayed lymphnode metastasis, 10 had distant metastasis. Thirty seven patients displayed recurrence and 12 patients died of disease.

Conclusion

PUNLMP is a frequent finding in young patients under 40 with bladder cancer. Nevertheless muscle invasive bladder cancer is also present and often a very aggressive disease. Patients should be treated according to the guidelines.