Validation of VitBOD, a simple burden of disease instrument for vitiligo

Main Article Content

Vaneeta Sheth Sujeeta Silwal


Background: Vitiligo is a chronic, progressive condition of skin depigmentation that has a negative impact on quality of life. 

Aim of the study:  To validate a novel, low-burden tool to more accurately assess the burden of disease on those affected. 

Methods: The VitBOD was designed as a ten question tool using visual analog scales to assess various physical, mental and emotional domains of health specific to vitiligo.  90 subjects with dermatologist-confirmed vitiligo agreed to complete the self-administered VitBOD questionnaire along with the previously validated Short Form-36 (SF-36). 

Results: 67 fully completed questionnaires were returned.  VitBOD scores were transformed to fit the direction of the SF-36 for statistical analysis.  Median overall scores were significantly lower for VitBOD as shown by the paired t-test (75.3 vs 85, p=0.015).  VitBOD showed high internal consistency (Cronbach’s alpha = 0.9).  Vitality, social, and mental health domains correlated positively with SF-36. 

Conclusion: VitBOD can reliably measure burden of disease in vitiligo as well as the SF-36 with distinct advantages being ease and speed of use along with disease-specificity.  Testing in broader patient populations would be useful for further validation. 

Article Details

How to Cite
SHETH, Vaneeta; SILWAL, Sujeeta. Validation of VitBOD, a simple burden of disease instrument for vitiligo. Medical Research Archives, [S.l.], n. 3, may 2015. ISSN 2375-1924. Available at: <>. Date accessed: 03 june 2023.
vitiligo; quality of life; burden of disease; mental health
Research Articles


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