Improving visualization of colorectal metastatic cancer using laparoscopic fluorescence-guided surgery

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PJ Steinkamp van der Zant F.A. Hentzen J.E.K.R. van Dam G.M. Kruijff S.


Extensive surgical treatment for peritoneal metastases originating from colorectal cancer provokes high morbidity and perioperative mortality rates, therefore careful and objective patient selection prior to such a procedure is crucial. Tumor-specific fluorescence-guided laparoscopy is a potential imaging technique for the improvement of patient selection. The aim is to select the patient that benefits the most of extensive and valuable surgical treatment, in terms of disease-free survival, overall survival and quality of life. Cancer-upregulated proteins and tumor-specific biological processes with matching fluorescence imaging agents could guide the surgeon to improved identification of malignant tissue during diagnostic laparoscopy and for detection of non-visible small tumor lesions during cytoreductive surgery.

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STEINKAMP, PJ et al. Improving visualization of colorectal metastatic cancer using laparoscopic fluorescence-guided surgery. Medical Research Archives, [S.l.], v. 8, n. 9, sep. 2020. ISSN 2375-1924. Available at: <>. Date accessed: 29 mar. 2023. doi:
Research Articles


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