Histopathological Spectrum of Cutaneous Lymphomas

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Published Nov 29, 2023
DOI: https://doi.org/10.18103/mra.v11i11.4712

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Main Article Content

A. Kaur Aminder Singh
Department of Pathology, Dayanand Medical College & Hospital, Ludhiana, Punjab, India
A. Singh Harpreet Kaur Bhavna Garg Vikram Narang

Abstract

Background: Cutaneous lymphomas are a heterogeneous group of extra-nodal non-Hodgkin’s lymphomas that are characterized by a cutaneous infiltration of malignant monoclonal lymphocytes. Less frequently, these lymphomas spread from the skin to the blood or a lymph node. The incidence of primary cutaneous lymphoma has been estimated to be 1:100,000 according to the World Health Organization. Usually, these lymphomas affect adults with a median age of 50 to 60 years. T-cell lymphomas predominate over primary B-cell lymphomas of the skin. The most important subtypes of cutaneous T cell lymphomas are Mycosis fungoides, Sezary syndrome, and primary cutaneous peripheral T cell lymphomas not otherwise specified. These subtypes present different clinical, histological, and molecular features, and can follow an indolent or a very aggressive course.


Aim: The aim of this study was to analyze cutaneous lymphomas to ascertain its clinical aspects including prevalence, histopathology and immune profile.


Material and methods: A retrospective analysis of skin biopsies over a 7-year period ranging from 2016 to 2022 was done, of which 11 cases were diagnosed as cutaneous lymphomas. These cases were analyzed in detail including immune profile.


Results & conclusions: The majority of the cases out of all cutaneous lymphomas were of T cell lymphoma and only one case was of B cell type. Definitive diagnosis of CTCL requires a multidisciplinary approach.


Keywords: cutaneous T cell lymphoma, cutaneous B cell lymphoma.

Article Details

How to Cite
KAUR, A. et al. Histopathological Spectrum of Cutaneous Lymphomas. Medical Research Archives, [S.l.], v. 11, n. 11, nov. 2023. ISSN 2375-1924. Available at: <https://esmed.org/MRA/mra/article/view/4712>. Date accessed: 16 may 2024. doi: https://doi.org/10.18103/mra.v11i11.4712.
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Issue
Vol 11 No 11 (2023): November Issue, Vol.11, Issue 11
Section
Research Articles

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