The Potential of Gene Editing Technologies in the Treatment of Hereditary Retinal Diseases

Abstract

Hereditary retinal diseases refers to a group of diseases caused by mutations in genes and which manifest through impairment of vision up to blindness. New gene editing technologies especially the CRISP-Cas9 have presented new therapeutic possibilities for these diseases ‎1 . This review looks into the prospects of using gene editing as a treatment for HRDs, the mechanisms behind the technology, their benefits and the therms that gene editing faces ‎2 Different methods of gene editing are examined together with the successes recorded in experimental models, and the adaptation of these to clinical practice ‎3‎,4 , Some of the issues raised include the efficacy, the future outlooks and the incorporation of gene editing in the normal practice of ophthalmic ‎5‎,6‎,7 . , Gene editing is an emerging science carries a great potential to transform the current approach to patients’ treatment, paving the way for a unique and effective treatment of HRD ‎