Abstract
Porocarcinoma, dermal duct tumor or malignant eccrine poroma also called malignant hidrocanthoma simplex is an infrequently reported skin malignancy that arises from the terminal ducts of the sweat gland. First described in 1963 by Pinkus & Mehregan. The term eccrine Porocarcinoma was coined by Mishima & Morioka. The reported incidence less than 1 per 100,000 persons years. Although commonly described in the palms and soles of the feet, it is the head neck followed by the lower extremities that are most affected. The etiology is unknown possible causes include radiation therapy, prolonged solar UV exposure and immunosuppression. The presentation is a painless slow growing red or pink nodular or ulcerative growth seen in the elderly males or females. The diagnosis therefore is delayed as it relies on the sum of Clinical, Histopathology and Immunohistological findings. Clinicians worldwide continue to be unfamiliar with this clinical condition. Masquerading as a benign appearing skin lesion they continue to deliberate on a myraid differential diagnosis from Bowen’s disease, amelanotic melanoma, seborrheic keratosis, fibroma, verruca vulgaris, pyogenic granuloma, and squamous cell carcinoma. Once advanced the prognosis of patients with metastatic Porocarcinoma (PC) continues to be grim, with little evidence based medicine on optimal management case reports will continue to highlight literature on this Masquerader.