Abstract
This retrospective case series reports on the use of an established alloplastic bone product composed of a 65:35 ratio of β Tricalcium Phosphate and Calcium Sulphate to facilitate host bone regeneration in a variety of intra-oral sites and clinical indications. The study involved seven patients treated by seven different clinicians operating at five geographical sites. All cases included trephined bone cores harvested at 12 and 33 weeks. These cores were subject to histological analysis using standardized protocols at six separate laboratories. The primary measured outcome was the percentage of residual graft, new bone, and connective tissue at the measured time points. The results of this case series suggest that the alloplastic bone product is 50% resorbed and replaced by new host bone at 12 weeks, with further consistent resorption to 85% at 33 weeks. These results suggest that this alloplastic product can be successfully used in a wide variety of intra-oral bone grafting protocols leading to consistent resorption of the material and its replacement with new host bone, independent of clinician and established histological analytical protocol used.