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01 · ABSTRACT

Abstract

BCP ALL is the most common phenotype of ALL.  Identification of recurrent genetic abnormalities specific for BCP-ALL [i.e., t(12;21), t(17;19), t(1;19)], has become an essential tool for confirmation of diagnosis and risk stratification. It can also be used for assessing response to treatment and for detecting the re-emergence of malignant cells. Although the definition of BCP ALL with recurrent genetic abnormalities can be correctly expressed in verbal terms, Mathematical Logic may provide a definition that is more concise. We defined the semantics of conjunctions by the truth values “1” or “0”. In a simplified syntax of English, the conjunctions “and”, “or”, “if and only if” were replaced by the symbols “∧ “, “V”, “↔” respectively. This method permitted definitions stripped from all ambiguous elements.

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02 · PUBLICATION RECORD

Article details

JournalMedical Research Archives
IssueVol 9 No 2 (2021): Volume 9 Issue 2, February, 2021
SectionResearch Articles
Published25 February 2021
DOI10.18103/mra.v9i2.2328
ISSN2375-1924
03 · RIGHTS & REUSE

Rights & reuse

This article is published under a Creative Commons Attribution License (CC BY 3.0) and may be shared or distributed by anyone as long as attribution is given to the journal.

Authors & affiliations

GZ

Gerhard Zugmaier

Department of Haematology, Oncology and Immunology, Pilipps University Marburg, Marburg, Germany

FL

Franco Locatelli

Pediatrics Sapienza, University of Rome, Director Department of Pediatric Hematology and Oncology IRCCS Ospedale Pediatrico Bambino Gesù, Rome, Italy

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