Psychosocial Basis of Human Sufferings and Poverty in Patients with Neurological and Psychiatric Disorders

Main Article Content

Souvik Dubey, MD, DM Ritwik Ghosh, MD Mahua Jana Dubey, MD Shambaditya Das, MD,DM Arka Prava Chakraborty, MD, DM Arindam Santra, MD, DM Ajitava Dutta, MD, DM Dipayan Roy, MD, DNB, PhD Alak Pandit, MD, DM Biman Kanti Roy, MD, DM Gautam Das, MD, DM Julián Benito-León, MD, PhD

Abstract

Neurological disorders and psychiatric ailments often lead to cognitive disabilities and low attainment of education, pivoting misconceptions, myths, and misbeliefs. Poverty and low educational attainment are intriguingly associated with poor awareness and perception of these diseases that add to the suffering. Poverty goes parallel with a low level of education and is intricately associated with neuropsychiatric ailments, which have the potential to spread transgenerationally. Robust education policies, proper government rules and regulations against the spread of disease-related myths and misconceptions, uplifting medical education in its true sense, voices against consanguinity, and programs to raise scientific perception about diseases can help to throw light at the end of this dark tunnel. In this article, the authors intend to 1) decipher the potential psychosocial basis of human suffering and poverty in patients with neurological and psychiatric disorders, and 2) discuss the apropos way-outs that would potentially mitigate suffering, and alleviate the economic burden and cognitive disabilities of families with neuropsychiatric diseases.

Keywords: Poverty, Human Suffering, Neurological disorders, Psychiatric disorders

Article Details

How to Cite
DUBEY, Souvik et al. Psychosocial Basis of Human Sufferings and Poverty in Patients with Neurological and Psychiatric Disorders. Medical Research Archives, [S.l.], v. 11, n. 5, may 2023. ISSN 2375-1924. Available at: <https://esmed.org/MRA/mra/article/view/3919>. Date accessed: 26 dec. 2024. doi: https://doi.org/10.18103/mra.v11i5.3919.
Section
Research Articles

References

1. Hoehe MR, Morris-Rosendahl DJ. The role of genetics and genomics in clinical psychiatry. Dialogues Clin Neurosci. 2018;20(3):169-177. doi:10.31887/DCNS.2018.20.3/mhoehe
2. Toft M. Advances in genetic diagnosis of neurological disorders. Acta Neurol Scand Suppl. 2014;(198):20-25. doi:10.1111/ane.12232
3. Dichgans M, Pulit SL, Rosand J. Stroke genetics: discovery, biology, and clinical applications. Lancet Neurol. 2019;18(6):587-599. doi:10.1016/S1474-4422(19)30043-2
4. Weber YG, Biskup S, Helbig KL, Von Spiczak S, Lerche H. The role of genetic testing in epilepsy diagnosis and management. Expert Rev Mol Diagn. 2017;17(8):739-750. doi:10.1080/14737159.2017.1335598
5. Axisa PP, Hafler DA. Multiple sclerosis: genetics, biomarkers, treatments. Curr Opin Neurol. 2016;29(3):345-353. doi:10.1097/WCO.0000000000000319
6. Coffey AJ, Durkie M, Hague S, et al. A genetic study of Wilson's disease in the United Kingdom. Brain. 2013;136(Pt 5):1476-1487. doi:10.1093/brain/awt035
7. Wamsley B, Geschwind DH. Functional genomics links genetic origins to pathophysiology in neurodegenerative and neuropsychiatric disease. Curr Opin Genet Dev. 2020;65:117-125. doi:10.1016/j.gde.2020.05.032
8. Finkbeiner S. Functional genomics, genetic risk profiling and cell phenotypes in neurodegenerative disease. Neurobiol Dis. 2020;146:105088. doi:10.1016/j.nbd.2020.105088
9. Sudhakar V, Richardson RM. Gene Therapy for Neurodegenerative Diseases. Neurotherapeutics. 2019;16(1):166-175. doi:10.1007/s13311-018-00694-0
10. Bertram L, Tanzi RE. The genetic epidemiology of neurodegenerative disease. J Clin Invest. 2005;115(6):1449-1457. doi:10.1172/JCI24761
11. Kovacs GG. Concepts and classification of neurodegenerative diseases. Handb Clin Neurol. 2017;145:301-307. doi:10.1016/B978-0-12-802395-2.00021-3
12. Anazi S, Maddirevula S, Salpietro V, et al. Expanding the genetic heterogeneity of intellectual disability [published correction appears in Hum Genet. 2017 Dec 29;:]. Hum Genet. 2017;136(11-12):1419-1429. doi:10.1007/s00439-017-1843-2
13. Han B, Pouget JG, Slowikowski K, et al. A method to decipher pleiotropy by detecting underlying heterogeneity driven by hidden subgroups applied to autoimmune and neuropsychiatric diseases. Nat Genet. 2016;48(7):803-810. doi:10.1038/ng.3572
14. Pichet Binette A, Vachon-Presseau É, Morris J, et al. Amyloid and Tau Pathology Associations With Personality Traits, Neuropsychiatric Symptoms, and Cognitive Lifestyle in the Preclinical Phases of Sporadic and Autosomal Dominant Alzheimer's Disease. Biol Psychiatry. 2021;89(8):776-785. doi:10.1016/j.biopsych.2020.01.023
15. Greenberg DR, Khandwala YS, Lu Y, Stevenson DK, Shaw GM, Eisenberg ML. Disease burden in offspring is associated with changing paternal demographics in the United States. Andrology. 2020;8(2):342-347. doi:10.1111/andr.12700
16. Everett Y, Martin CG, Zalewski M. A Systematic Review Focusing on Psychotherapeutic Interventions that Impact Parental Psychopathology, Child Psychopathology and Parenting Behavior. Clin Child Fam Psychol Rev. 2021;24(3):579-598. doi:10.1007/s10567-021-00355-3
17. Calkins SD, Propper C, Mills-Koonce WR. A biopsychosocial perspective on parenting and developmental psychopathology. Dev Psychopathol. 2013;25(4 Pt 2):1399-1414. doi:10.1017/S0954579413000680
18. Hartman L, Jenkinson C, Morley D. Young People's Response to Parental Neurological Disorder: A Structured Review. Adolesc Health Med Ther. 2020;11:39-51. Published 2020 Mar 26. doi:10.2147/AHMT.S237807
19. Rodenburg R, Meijer AM, Scherphof C, et al. Parenting and restrictions in childhood epilepsy. Epilepsy Behav. 2013;27(3):497-503. doi:10.1016/j.yebeh.2013.01.026
20. Huber-Mollema Y, Oort FJ, Lindhout D, Rodenburg R. Well-being of mothers with epilepsy with school-aged children. Epilepsy Behav. 2020;105:106966. doi:10.1016/j.yebeh.2020.106966
21. Rodenburg R, Meijer AM, Deković M, Aldenkamp AP. Family factors and psychopathology in children with epilepsy: a literature review. Epilepsy Behav. 2005;6(4):488-503. doi:10.1016/j.yebeh.2005.03.006
22. Adewuya AO. Parental psychopathology and self-rated quality of life in adolescents with epilepsy in Nigeria. Dev Med Child Neurol. 2006;48(7):600-603. doi:10.1017/S0012162206001253
23. Xie S, Karlsson H, Dalman C, et al. Family History of Mental and Neurological Disorders and Risk of Autism. JAMA Netw Open. 2019;2(3):e190154. Published 2019 Mar 1. doi:10.1001/jamanetworkopen.2019.0154
24. Romero-Gonzalez M, Chandler S, Simonoff E. The relationship of parental expressed emotion to co-occurring psychopathology in individuals with autism spectrum disorder: A systematic review. Res Dev Disabil. 2018;72:152-165. doi:10.1016/j.ridd.2017.10.022
25. Thomas PA, King JS, Mendelson JL, Nelson-Gray RO. Parental psychopathology and expectations for the futures of children with autism spectrum disorder. J Appl Res Intellect Disabil. 2018;31(1):98-105. doi:10.1111/jar.12337
26. Midouhas E, Yogaratnam A, Flouri E, Charman T. Psychopathology trajectories of children with autism spectrum disorder: the role of family poverty and parenting. J Am Acad Child Adolesc Psychiatry. 2013;52(10):1057-1065.e1. doi:10.1016/j.jaac.2013.07.011
27. Propper L, Sandstrom A, Rempel S, et al. Attention-deficit/hyperactivity disorder and other neurodevelopmental disorders in offspring of parents with depression and bipolar disorder [published online ahead of print, 2021 Jun 18]. Psychol Med. 2021;1-8. doi:10.1017/S0033291721001951
28. Yu D, Mathews CA, Scharf JM, et al. Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD. Am J Psychiatry. 2015;172(1):82-93. doi:10.1176/appi.ajp.2014.13101306
29. Brem S, Grünblatt E, Drechsler R, Riederer P, Walitza S. The neurobiological link between OCD and ADHD. Atten Defic Hyperact Disord. 2014;6(3):175-202. doi:10.1007/s12402-014-0146-x
30. Thapar A, Cooper M, Rutter M. Neurodevelopmental disorders. Lancet Psychiatry. 2017;4(4):339-346. doi:10.1016/S2215-0366(16)30376-5
31. Sudre G, Frederick J, Sharp W, et al. Mapping associations between polygenic risks for childhood neuropsychiatric disorders, symptoms of attention deficit hyperactivity disorder, cognition, and the brain. Mol Psychiatry. 2020;25(10):2482-2492. doi:10.1038/s41380-019-0350-3
32. Adedokun ST, Yaya S. Factors influencing mothers' health care seeking behaviour for their children: evidence from 31 countries in sub-Saharan Africa. BMC Health Serv Res. 2020;20(1):842. Published 2020 Sep 7. doi:10.1186/s12913-020-05683-8
33. Currie G, Szabo J. Social isolation and exclusion: the parents' experience of caring for children with rare neurodevelopmental disorders. Int J Qual Stud Health Well-being. 2020;15(1):1725362. doi:10.1080/17482631.2020.1725362
34. Taylor JJ, Williams NR, George MS. Beyond neural cubism: promoting a multidimensional view of brain disorders by enhancing the integration of neurology and psychiatry in education. Acad Med. 2015;90(5):581-586. doi:10.1097/ACM.0000000000000530
35. Benjamin S. Neuropsychiatry and neural cubism. Acad Med. 2015;90(5):556-558. doi:10.1097/ACM.0000000000000531
36. Bandstra NF, Camfield CS, Camfield PR. Stigma of epilepsy. Can J Neurol Sci. 2008;35(4):436-440. doi:10.1017/s0317167100009082
37. Bou Nasif M, Koubeissi M, Azar NJ. Epilepsy - from mysticism to science. Rev Neurol (Paris). 2021;177(9):1047-1058. doi:10.1016/j.neurol.2021.01.021
38. Javed A, Lee C, Zakaria H, et al. Reducing the stigma of mental health disorders with a focus on low- and middle-income countries. Asian J Psychiatr. 2021;58:102601. doi:10.1016/j.ajp.2021.102601
39. Whelan CD, Altmann A, Botía JA, et al. Structural brain abnormalities in the common epilepsies assessed in a worldwide ENIGMA study. Brain. 2018;141(2):391-408. doi:10.1093/brain/awx341
40. Mora P, Hollier PL, Guimbal S, et al. Blood-brain barrier genetic disruption leads to protective barrier formation at the Glia Limitans. PLoS Biol. 2020;18(11):e3000946. Published 2020 Nov 30. doi:10.1371/journal.pbio.3000946
41. Torres-Muñoz J, Fonseca-Perez JE, Laurent K. Biological and Psychosocial Factors, Risk Behaviors, and Perinatal Asphyxia in a University Hospital: Matched Case-Control Study, Cali, Colombia (2012-2014). Front Public Health. 2021;9:535737. Published 2021 Jun 21. doi:10.3389/fpubh.2021.535737
42. Jahan S. Poverty and infant mortality in the Eastern Mediterranean region: a meta-analysis. J Epidemiol Community Health. 2008;62(8):745-751. doi:10.1136/jech.2007.068031
43. Schiariti V, Simeonsson RJ, Hall K. Promoting Developmental Potential in Early Childhood: A Global Framework for Health and Education. Int J Environ Res Public Health. 2021;18(4):2007. Published 2021 Feb 19. doi:10.3390/ijerph18042007
44. Ho-Wai So S, Hoi-Kei Chan G, Kit-Wa Wong C, et al. A randomised controlled trial of metacognitive training for psychosis, depression, and belief flexibility. J Affect Disord. 2021;279:388-397. doi:10.1016/j.jad.2020.09.126
45. Hoge SK, Appelbaum PS. Ethics and neuropsychiatric genetics: a review of major issues. Int J Neuropsychopharmacol. 2012;15(10):1547-1557. doi:10.1017/S1461145711001982
46. Loi S, Chiu E. Witchcraft and Huntington's disease: a salutary history of societal and medical stigmatisation. Australas Psychiatry. 2012;20(5):438-441. doi:10.1177/1039856212459587
47. Smoller JW, Andreassen OA, Edenberg HJ, Faraone SV, Glatt SJ, Kendler KS. Psychiatric genetics and the structure of psychopathology [published correction appears in Mol Psychiatry. 2018 Mar 14;:]. Mol Psychiatry. 2019;24(3):409-420. doi:10.1038/s41380-017-0010-4
48. Ahmed HM, Advani R, Arif AA, Khan S. An Assessment of the Knowledge, Attitudes, and Practices of Patients and Families with Diagnoses of Hereditary Neuromuscular Disorders. Neuroepidemiology. 2020;54(3):265-271. doi:10.1159/000505330
49. Mayor R, Gunn S, Reuber M, Simpson J. Experiences of stigma in people with epilepsy: A meta-synthesis of qualitative evidence. Seizure. 2022;94:142-160. doi:10.1016/j.seizure.2021.11.021
50. Terracciano A, Aschwanden D, Stephan Y, et al. Neuroticism and Risk of Parkinson's Disease: A Meta-Analysis. Mov Disord. 2021;36(8):1863-1870. doi:10.1002/mds.28575
51. Terracciano A, Sutin AR. Personality and Alzheimer's disease: An integrative review. Personal Disord. 2019;10(1):4-12. doi:10.1037/per0000268
52. Terracciano A, Aschwanden D, Passamonti L, et al. Is neuroticism differentially associated with risk of Alzheimer's disease, vascular dementia, and frontotemporal dementia?. J Psychiatr Res. 2021;138:34-40. doi:10.1016/j.jpsychires.2021.03.039
53. Dubey S, Dubey MJ, Ghosh R, Mukherjee D, Pandit A, Benito-León J. Behavioral and psychological symptoms in neurodegenerative dementias: harbinger, follower, or constant collateral?. Egypt J Neurol Psychiatr Neurosurg. 2022;58:102. doi:10.1186/s41983-022-00538-x
54. Lazar M, Davenport L. Barriers to Health Care Access for Low Income Families: A Review of Literature. J Community Health Nurs. 2018;35(1):28-37. doi:10.1080/07370016.2018.1404832
55. Patel V, Kleinman A. Poverty and common mental disorders in developing countries. Bull World Health Organ. 2003;81(8):609-615.
56. Nieuwenhuis J, Kleinepier T, van Ham M. The Role of Exposure to Neighborhood and School Poverty in Understanding Educational Attainment. J Youth Adolesc. 2021;50(5):872-892. doi:10.1007/s10964-021-01427-x
57. Porterfield SL, McBride TD. The effect of poverty and caregiver education on perceived need and access to health services among children with special health care needs. Am J Public Health. 2007;97(2):323-329. doi:10.2105/AJPH.2004.055921
58. Barnish MS, Tan SY, Taeihagh A, Tørnes M, Nelson-Horne RVH, Melendez-Torres GJ. Linking political exposures to child and maternal health outcomes: a realist review. BMC Public Health. 2021;21(1):127. Published 2021 Jan 12. doi:10.1186/s12889-021-10176-2
59. Kuss DJ, Griffiths MD. Online social networking and addiction--a review of the psychological literature. Int J Environ Res Public Health. 2011;8(9):3528-3552. doi:10.3390/ijerph8093528
60. Kwak MJ, Cho H, Kim DJ. The Role of Motivation Systems, Anxiety, and Low Self-Control in Smartphone Addiction among Smartphone-Based Social Networking Service (SNS) Users. Int J Environ Res Public Health. 2022;19(11):6918. Published 2022 Jun 5. doi:10.3390/ijerph19116918
61. Hudson G, Jansli SM, Erturk S, et al. Investigation of Carers' Perspectives of Dementia Misconceptions on Twitter: Focus Group Study. JMIR Aging. 2022;5(1):e30388. Published 2022 Jan 24. doi:10.2196/30388
62. Patil AU, Madathil D, Huang CM. Age-related and individual variations in altered prefrontal and cerebellar connectivity associated with the tendency of developing internet addiction. Hum Brain Mapp. 2021;42(14):4525-4537. doi:10.1002/hbm.25562
63. Sjölund S, Allebeck P, Hemmingsson T. Intelligence quotient (IQ) in adolescence and later risk of alcohol-related hospital admissions and deaths--37-year follow-up of Swedish conscripts. Addiction. 2012;107(1):89-97. doi:10.1111/j.1360-0443.2011.03544.x
64. Bailey AJ, Gerst K, Finn PR. Intelligence moderates the relationship between delay discounting rate and problematic alcohol use. Psychol Addict Behav. 2020;34(1):175-181. doi:10.1037/adb0000471
65. Bart CP, Nusslock R, Ng TH, et al. Decreased reward-related brain function prospectively predicts increased substance use. J Abnorm Psychol. 2021;130(8):886-898. doi:10.1037/abn0000711
66. Müller SM, Schiebener J, Brand M, Liebherr M. Decision-making, cognitive functions, impulsivity, and media multitasking expectancies in high versus low media multitaskers. Cogn Process. 2021;22(4):593-607. doi:10.1007/s10339-021-01029-2
67. Welte JW, Wieczorek WF. Alcohol, intelligence and violent crime in young males. J Subst Abuse. 1998;10(3):309-319. doi:10.1016/s0899-3289(99)00002-4
68. Dubey MJ, Ghosh R, Chatterjee S, Biswas P, Chatterjee S, Dubey S. COVID-19 and addiction. Diabetes Metab Syndr. 2020;14(5):817-823. doi:10.1016/j.dsx.2020.06.008
69. Moulding R, Kyrios M. Anxiety disorders and control related beliefs: the exemplar of Obsessive-Compulsive Disorder (OCD). Clin Psychol Rev. 2006;26(5):573-583. doi:10.1016/j.cpr.2006.01.009
70. Hezel DM, McNally RJ. A Theoretical review of cognitive biases and deficits in obsessive-compulsive disorder. Biol Psychol. 2016;121(Pt B):221-232. doi:10.1016/j.biopsycho.2015.10.012
71. Olatunji BO, Christian C, Brosof L, Tolin DF, Levinson CA. What is at the core of OCD? A network analysis of selected obsessive-compulsive symptoms and beliefs. J Affect Disord. 2019;257:45-54. doi:10.1016/j.jad.2019.06.064
72. Tümkaya S, Karadağ F, Yenigün EH, Özdel O, Kashyap H. Metacognitive Beliefs and Their Relation with Symptoms in Obsessive-Compulsive Disorder. Noro Psikiyatr Ars. 2018;55(4):358-363. doi:10.29399/npa.22655
73. Mathieu SL, Conlon EG, Waters AM, McKenzie ML, Farrell LJ. Inflated Responsibility Beliefs in Paediatric OCD: Exploring the Role of Parental Rearing and Child Age. Child Psychiatry Hum Dev. 2020;51(4):552-562. doi:10.1007/s10578-019-00938-w
74. Pugh K, Luzon O, Ellett L. Responsibility beliefs and persecutory delusions. Psychiatry Res. 2018;259:340-344. doi:10.1016/j.psychres.2017.10.044
75. Dar R, Kahn DT, Carmeli R. The relationship between sensory processing, childhood rituals and obsessive-compulsive symptoms. J Behav Ther Exp Psychiatry. 2012;43(1):679-684. doi:10.1016/j.jbtep.2011.09.008
76. Dubey S, Dubey MJ, Ghosh R, et al. The cognitive basis of psychosocial impact in COVID-19 pandemic. Does it encircle the default mode network of the brain? A pragmatic proposal. Med Res Arch. 2022;10(3):10.18103/mra.v10i3.2707. doi:10.18103/mra.v10i3.2707
77. Burgers JS. Opschudding over evidencebased medicine: van reductionisme naar realisme in de toepassing van richtlijnen [Criticism of evidence-based medicine: from reductionism to realism in the application of guidelines]. Ned Tijdschr Geneeskd. 2015;159:A8376.
78. Kouimtsidis Ch, John-Smith S, Kemp P, Ikkos G. Evidence based mental healthcare and service innovation: review of concepts and challenges. Psychiatriki. 2013;24(1):45-54.
79. Rogers WA. Evidence based medicine and justice: a framework for looking at the impact of EBM upon vulnerable or disadvantaged groups. J Med Ethics. 2004;30(2):141-145. doi:10.1136/jme.2003.007062
80. Alemayehu C, Mitchell G, Nikles J. Barriers for conducting clinical trials in developing countries- a systematic review. Int J Equity Health. 2018;17(1):37. Published 2018 Mar 22. doi:10.1186/s12939-018-0748-6
81. Rahman MM, Ghoshal UC, Ragunath K, et al. Biomedical research in developing countries: Opportunities, methods, and challenges. Indian J Gastroenterol. 2020;39(3):292-302. doi:10.1007/s12664-020-01056-5
82. Sumathipala A, Siribaddana S, Patel V. Under-representation of developing countries in the research literature: ethical issues arising from a survey of five leading medical journals. BMC Med Ethics. 2004;5:E5. Published 2004 Oct 4. doi:10.1186/1472-6939-5-5
83. Emanuel EJ, Wendler D, Killen J, Grady C. What makes clinical research in developing countries ethical? The benchmarks of ethical research. J Infect Dis. 2004;189(5):930-937. doi:10.1086/381709
84. Noor RA. Health research oversight in Africa. Acta Trop. 2009;112 Suppl 1:S63-S70. doi:10.1016/j.actatropica.2009.08.019
85. Kanoute A, Faye D, Bourgeois D. Current status of oral health research in Africa: an overview. Int Dent J. 2012;62(6):301-307. doi:10.1111/j.1875-595X.2012.00123x
86. Sharan P, Gallo C, Gureje O, et al. Mental health research priorities in low- and middle-income countries of Africa, Asia, Latin America and the Caribbean. Br J Psychiatry. 2009;195(4):354-363. doi:10.1192/bjp.bp.108.050187
87. Ghosh R., Roy D., Benito-León J. Indigenous medical practitioners to curb coronavirus disease-19 crisis in India: a pragmatic proposal? Indian J Commun Med. 2022 doi: 10.4103/ijcm.ijcm_997_21.
88. Upenieks L, Ford-Robertson J, Robertson JE. Trust in God and/or Science? Sociodemographic Differences in the Effects of Beliefs in an Engaged God and Mistrust of the COVID-19 Vaccine. J Relig Health. 2022;61(1):657-686. doi:10.1007/s10943-021-01466-5
89. Sharath S. Doctors in India suffer from a God complex. Indian J Med Ethics. 2008;5(3):149. doi:10.20529/IJME.2008.054
90. Cotton S, Puchalski CM, Sherman SN, et al. Spirituality and religion in patients with HIV/AIDS [published correction appears in J Gen Intern Med. 2009 Aug;24(8):994]. J Gen Intern Med. 2006;21 Suppl 5(Suppl 5):S5-S13. doi:10.1111/j.1525-1497.2006.00642.x
91. Klitzman R. Doctor, Will You Pray for Me? Responding to Patients' Religious and Spiritual Concerns. Acad Med. 2021;96(3):349-354. doi:10.1097/ACM.0000000000003765
92. Superdock AK, Barfield RC, Brandon DH, Docherty SL. Exploring the vagueness of Religion & Spirituality in complex pediatric decision-making: a qualitative study. BMC Palliat Care. 2018;17(1):107. Published 2018 Sep 12. doi:10.1186/s12904-018-0360-y
93. Gross M. Between Party, People, and Profession: The Many Faces of the 'Doctor' during the Cultural Revolution. Med Hist. 2018;62(3):333-359. doi:10.1017/mdh.2018.23
94. Dornan T, Roy Bentley S, Kelly M. Medical teachers' discursive positioning of doctors in relation to patients. Med Educ. 2020;54(7):628-636. doi:10.1111/medu.14074
95. Szaflarski M, Ritchey PN, Leonard AC, et al. Modeling the effects of spirituality/religion on patients' perceptions of living with HIV/AIDS. J Gen Intern Med. 2006;21 Suppl 5(Suppl 5):S28-S38. doi:10.1111/j.1525-1497.2006.00646.x
96. Freeman-Ferguson M. Tourette's syndrome: challenging misconceptions and improving understanding. Nurs Child Young People. 2022;34(5):34-42. doi:10.7748/ncyp.2022.e1416
97. Li M, Santpere G, Imamura Kawasawa Y, et al. Integrative functional genomic analysis of human brain development and neuropsychiatric risks. Science. 2018;362(6420):eaat7615. doi:10.1126/science.aat7615
98. Ueda K, Black KJ. A Comprehensive Review of Tic Disorders in Children. J Clin Med. 2021;10(11):2479. Published 2021 Jun 3. doi:10.3390/jcm10112479
99. Kaddumukasa M, Smith PJ, Kaddumukasa MN, et al. Epilepsy beliefs and misconceptions among patient and community samples in Uganda. Epilepsy Behav. 2021;114(Pt B):107300. doi:10.1016/j.yebeh.2020.107300
100. Herrmann LK, Welter E, Berg AT, Perzynski AT, Van Doren JR, Sajatovic M. Epilepsy misconceptions and stigma reduction: Current status in Western countries. Epilepsy Behav. 2016;60:165-173. doi:10.1016/j.yebeh.2016.04.003
101. Grabowski DC, Fishman J, Wild I, Lavin B. Changing the neurology policy landscape in the United States: Misconceptions and facts about epilepsy. Health Policy. 2018;122(7):797-802. doi:10.1016/j.healthpol.2018.05.012
102. Mohanty M, Beaulieu F, Sampath S, Tambunan D, Kataria S, Rosman NP. "Your Child Has Cerebral Palsy": Parental Understanding and Misconceptions. J Child Neurol. 2021;36(8):648-654. doi:10.1177/0883073821991300
103. Sansa E, Fray S, Jamoussi H, et al. Knowledge and attitudes toward epilepsy among teachers in Tunisia. Epilepsy Behav. 2021;123:108260. doi:10.1016/j.yebeh.2021.108260
104. Andersson K, Strang S, Zelano J, Chaplin J, Malmgren K, Ozanne A. Multiple stigma among first-generation immigrants with epilepsy in Sweden. Epilepsy Behav. 2021;115:107638. doi:10.1016/j.yebeh.2020.107638
105. Cox JH, Nahar A, Termine C, et al. Social stigma and self-perception in adolescents with tourette syndrome. Adolesc Health Med Ther. 2019;10:75-82. Published 2019 Jun 11. doi:10.2147/AHMT.S175765
106. Agha SS, Zammit S, Thapar A, Langley K. Maternal psychopathology and offspring clinical outcome: a four-year follow-up of boys with ADHD. Eur Child Adolesc Psychiatry. 2017;26(2):253-262. doi:10.1007/s00787-016-0873-y
107. Sellers R, Harold GT, Thapar A, et al. Examining the Role of Genetic Risk and Longitudinal Transmission Processes Underlying Maternal Parenting and Psychopathology and Children's ADHD Symptoms and Aggression: Utilizing the Advantages of a Prospective Adoption Design [published correction appears in Behav Genet. 2021 Jul;51(4):440]. Behav Genet. 2020;50(4):247-262. doi:10.1007/s10519-020-10006-y
108. Rusengamihigo D, Mutabaruka J, Biracyaza E, Magalakaki O, El'Husseini M. Parental mental illness and their offspring's mental health in Rwanda: neuropsychiatric hospital of Rwanda. BMC Psychol. 2021;9(1):135. Published 2021 Sep 4. doi:10.1186/s40359-021-00633-3
109. Yu J, Patel RA, Gilman SE. Childhood disadvantage, neurocognitive development and neuropsychiatric disorders: Evidence of mechanisms. Curr Opin Psychiatry. 2021;34(3):306-323. doi:10.1097/YCO.0000000000000701
110. Al Jumah M, Al Malik Y, AlKhawajah NM, et al. Family Planning for People with Multiple Sclerosis in Saudi Arabia: an Expert Consensus. Mult Scler Int. 2021;2021:6667006. Published 2021 Feb 15. doi:10.1155/2021/6667006
111. Johnson MR, Shorvon SD. Heredity in epilepsy: neurodevelopment, comorbidity, and the neurological trait. Epilepsy Behav. 2011;22(3):421-427. doi:10.1016/j.yebeh.2011.07.031
112. Heinzen EL, Neale BM, Traynelis SF, Allen AS, Goldstein DB. The genetics of neuropsychiatric diseases: looking in and beyond the exome. Annu Rev Neurosci. 2015;38:47-68. doi:10.1146/annurev-neuro-071714-034136
113. Ahlskog JE. Common Myths and Misconceptions That Sidetrack Parkinson Disease Treatment, to the Detriment of Patients. Mayo Clin Proc. 2020;95(10):2225-2234. doi:10.1016/j.mayocp.2020.02.006
114. Salinas MR, Chambers EJ, Ho T, et al. Patient perceptions and knowledge of Parkinson's disease and treatment (KnowPD). Clin Park Relat Disord. 2020;3:100038. Published 2020 Jan 16. doi:10.1016/j.prdoa.2020.100038
115. Jones HJ, Heron J, Hammerton G, et al. Investigating the genetic architecture of general and specific psychopathology in adolescence. Transl Psychiatry. 2018;8(1):145. Published 2018 Aug 8. doi:10.1038/s41398-018-0204-9
116. Healey ML, Grossman M. Cognitive and Affective Perspective-Taking: Evidence for Shared and Dissociable Anatomical Substrates. Front Neurol. 2018;9:491. Published 2018 Jun 25. doi:10.3389/fneur.2018.00491
117. van Dijk MT, Murphy E, Posner JE, Talati A, Weissman MM. Association of Multigenerational Family History of Depression With Lifetime Depressive and Other Psychiatric Disorders in Children: Results from the Adolescent Brain Cognitive Development (ABCD) Study. JAMA Psychiatry. 2021;78(7):778-787. doi:10.1001/jamapsychiatry.2021.0350
118. Schapira AH, Olanow CW. Neuroprotection in Parkinson disease: mysteries, myths, and misconceptions. JAMA. 2004;291(3):358-364. doi:10.1001/jama.291.3.358
119. Niarchou M, Zammit S, Lewis G. The Avon Longitudinal Study of Parents and Children (ALSPAC) birth cohort as a resource for studying psychopathology in childhood and adolescence: a summary of findings for depression and psychosis. Soc Psychiatry Psychiatr Epidemiol. 2015;50(7):1017-1027. doi:10.1007/s00127-015-1072-8
120. Spadoni AD, Vinograd M, Cuccurazzu B, et al. Contribution of early-life unpredictability to neuropsychiatric symptom patterns in adulthood. Depress Anxiety. 2022;39(10-11):706-717. doi:10.1002/da.23277
121. de Boer A, Vermeulen K, Egger JIM, et al. EHMT1 mosaicism in apparently unaffected parents is associated with autism spectrum disorder and neurocognitive dysfunction. Mol Autism. 2018;9:5. Published 2018 Jan 25. doi:10.1186/s13229-018-0193-9
122. Marathe S, Hunter BM, Chakravarthi I, Shukla A, Murray SF. The impacts of corporatisation of healthcare on medical practice and professionals in Maharashtra, India. BMJ Glob Health. 2020;5(2):e002026. Published 2020 Feb 11. doi:10.1136/bmjgh-2019-002026
123. Turner S, Wright JS. The corporatization of healthcare organizations internationally: A scoping review of processes, impacts, and mediators. Public Administration. 2022 Jun;100(2):308-23.
124. Harding, April; Preker, Alexander S.. 2000. The Corporatization of Public Hospitals. HNP discussion paper series;. World Bank, Washington, DC. © World Bank. https://openknowledge.worldbank.org/handle/10986/13694 License: CC BY 3.0 IGO
125. Virk A, Croke K, Mohd Yusoff M, et al. Hybrid Organizations in Health Systems: The Corporatization of Malaysia's National Heart Institute. Health Syst Reform. 2020;6(1):e1833639. doi:10.1080/23288604.2020.1833639
126. Helmchen H. Ethische Implikationen der Neurowissenschaften in der Klinik [Ethical aspects of clinical neuroscience]. Nervenarzt. 2000;71(9):700-708. doi:10.1007/s001150050653
127. Cotter K, Siskind CE, Sha SJ, Hanson-Kahn AK. Positive Attitudes and Therapeutic Misconception Around Hypothetical Clinical Trial Participation in the Huntington's Disease Community. J Huntingtons Dis. 2019;8(4):421-430. doi:10.3233/JHD-190382
128. Castillo EG, Ijadi-Maghsoodi R, Shadravan S, et al. Community Interventions to Promote Mental Health and Social Equity. Curr Psychiatry Rep. 2019;21(5):35. Published 2019 Mar 29. doi:10.1007/s11920-019-1017-0
129. Martin LT, Plough A, Carman KG, Leviton L, Bogdan O, Miller CE. Strengthening Integration Of Health Services And Systems. Health Aff (Millwood). 2016;35(11):1976-1981. doi:10.1377/hlthaff.2016.0605
130. Álvarez-Díaz JA. Neuroetica como neurociencia de la etica [Neuroethics as the neuroscience of ethics]. Rev Neurol. 2013;57(8):374-382.
131. Racine E, Dubljević V, Jox RJ, et al. Can Neuroscience Contribute to Practical Ethics? A Critical Review and Discussion of the Methodological and Translational Challenges of the Neuroscience of Ethics. Bioethics. 2017;31(5):328-337. doi:10.1111/bioe.12357
132. Figueroa G. Neuroethics: the pursuit of transforming medical ethics in scientific ethics. Biol Res. 2016;49:11. Published 2016 Feb 20. doi:10.1186/s40659-016-0070-y
133. Decety J, Yoder KJ. The Emerging Social Neuroscience of Justice Motivation. Trends Cogn Sci. 2017;21(1):6-14. doi:10.1016/j.tics.2016.10.008
134. Sobański JA, Dudek D. Psychiatry and neurology: from dualism to integration. Neurol Neurochir Pol. 2013;47(6):577-583. doi:10.5114/ninp.2013.39069
135. Taylor JJ, Williams NR, George MS. Beyond neural cubism: promoting a multidimensional view of brain disorders by enhancing the integration of neurology and psychiatry in education. Acad Med. 2015;90(5):581-586. doi:10.1097/ACM.0000000000000530
136. Sachdev P, Mohan A. An International Curriculum for Neuropsychiatry and Behavioural Neurology. Rev Colomb Psiquiatr. 2017;46 Suppl 1:18-27. doi:10.1016/j.rcp.2017.05.001
137. Trapp NT, Martyna MR, Siddiqi SH, Bajestan SN. The Neuropsychiatric Approach to the Assessment of Patients in Neurology. Semin Neurol. 2022;42(2):88-106. doi:10.1055/s-0042-1745741
138. Schildkrout B, Benjamin S, Lauterbach MD. Integrating Neuroscience Knowledge and Neuropsychiatric Skills Into Psychiatry: The Way Forward. Acad Med. 2016;91(5):650-656. doi:10.1097/ACM.0000000000001003
139. Benjamin S, Widge A, Shaw K. Neuropsychiatry and neuroscience milestones for general psychiatry trainees. Acad Psychiatry. 2014;38(3):275-282. doi:10.1007/s40596-014-0112-0
140. Coverdale J, Balon R, Beresin EV, et al. Teaching clinical neuroscience to psychiatry residents: model curricula. Acad Psychiatry. 2014;38(2):111-115. doi:10.1007/s40596-014-0045-7
141. Gopalan P, Azzam PN, Travis MJ, Schlesinger A, Lewis DA. Longitudinal interdisciplinary neuroscience curriculum. Acad Psychiatry. 2014;38(2):163-167. doi:10.1007/s40596-014-0049-3
142. Cooper JJ, Korb AS, Akil M. Bringing Neuroscience to the Bedside. Focus (Am Psychiatr Publ). 2019;17(1):2-7. doi:10.1176/appi.focus.20180033
143. Sachdev PS, Mohan A. Neuropsychiatry: where are we and where do we go from here?. Mens Sana Monogr. 2013;11(1):4-15. doi:10.4103/0973-1229.109282
144. Fogel BS, Schiffer RB. Defining neuropsychiatry: professional activities and opinions of psychiatrist-neurologists with dual certification. J Neuropsychiatry Clin Neurosci. 1989;1(2):173-175. doi:10.1176/jnp.1.2.173
145. Ibáñez A, García AM, Esteves S, et al. Social neuroscience: undoing the schism between neurology and psychiatry. Soc Neurosci. 2018;13(1):1-39. doi:10.1080/17470919.2016.1245214
146. Perez DL, Keshavan MS, Scharf JM, Boes AD, Price BH. Bridging the Great Divide: What Can Neurology Learn From Psychiatry?. J Neuropsychiatry Clin Neurosci. 2018;30(4):271-278. doi:10.1176/appi.neuropsych.17100200
147. Lee TS, Ng BY, Lee WL. Neuropsychiatry--an emerging field. Ann Acad Med Singap. 2008;37(7):601-605.
148. Fricchione GL. Evolving a new neuropsychiatry. Dialogues Clin Neurosci. 2018;20(2):141-145. doi:10.31887/DCNS.2018.20.2/gfricchione
149. Van Oudenhove L, Cuypers SE. The philosophical "mind-body problem" and its relevance for the relationship between psychiatry and the neurosciences. Perspect Biol Med. 2010;53(4):545-557. doi:10.1353/pbm.2010.0012
150. Frisch S. Are Mental Disorders Brain Diseases, and What Does This Mean? A Clinical-Neuropsychological Perspective. Psychopathology. 2016;49(3):135-142. doi:10.1159/000447359
151. Frisch S. Why Biological Psychiatry Hasn't Delivered Yet - and Why Neurology Knows. Psychiatry Investig. 2021;18(12):1145-1148. doi:10.30773/pi.2021.0258
152. Martin JB. The integration of neurology, psychiatry, and neuroscience in the 21st century. Am J Psychiatry. 2002;159(5):695-704. doi:10.1176/appi.ajp.159.5.695
153. Northoff G. Neuropsychiatry. An old discipline in a new gestalt bridging biological psychiatry, neuropsychology, and cognitive neurology. Eur Arch Psychiatry Clin Neurosci. 2008;258(4):226-238. doi:10.1007/s00406-007-0783-6
154. Peled A. Plasticity imbalance in mental disorders the neuroscience of psychiatry: implications for diagnosis and research. Med Hypotheses. 2005;65(5):947-952. doi:10.1016/j.mehy.2005.05.007
155. Kaushik A, Kostaki E, Kyriakopoulos M. The stigma of mental illness in children and adolescents: A systematic review. Psychiatry Res. 2016;243:469-494. doi:10.1016/j.psychres.2016.04.042
156. Oexle N, Waldmann T, Staiger T, Xu Z, Rüsch N. Mental illness stigma and suicidality: the role of public and individual stigma. Epidemiol Psychiatr Sci. 2018;27(2):169-175. doi:10.1017/S2045796016000949
157. Avdibegović E, Hasanović M. The Stigma of Mental Illness and Recovery. Psychiatr Danub. 2017;29(Suppl 5):900-905.
158. Corrigan PW, Rao D. On the self-stigma of mental illness: stages, disclosure, and strategies for change. Can J Psychiatry. 2012;57(8):464-469. doi:10.1177/070674371205700804
159. Abdullah T, Brown TL. Mental illness stigma and ethnocultural beliefs, values, and norms: an integrative review. Clin Psychol Rev. 2011;31(6):934-948. doi:10.1016/j.cpr.2011.05.003
160. Bravo-Mehmedbašić A, Kučukalić S. Stigma of psychiatric diseases and psychiatry. Psychiatr Danub. 2017;29(Suppl 5):877-879.
161. Tyerman J, Patovirta AL, Celestini A. How Stigma and Discrimination Influences Nursing Care of Persons Diagnosed with Mental Illness: A Systematic Review. Issues Ment Health Nurs. 2021;42(2):153-163. doi:10.1080/01612840.2020.1789788
162. Tedrus GMAS, Pereira RB, Zoppi M. Epilepsy, stigma, and family. Epilepsy Behav. 2018;78:265-268. doi:10.1016/j.yebeh.2017.08.007
163. Stangl AL, Earnshaw VA, Logie CH, et al. The Health Stigma and Discrimination Framework: a global, crosscutting framework to inform research, intervention development, and policy on health-related stigmas. BMC Med. 2019;17(1):31. Published 2019 Feb 15. doi:10.1186/s12916-019-1271-3

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